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DAHANCA 33: Image Guided Dose-escalated Radiotherapy to Patients With Hypoxic HNSCC

2016-11-30 15:45:38 | BioPortfolio

Summary

Aim: To improve curability of radiotherapy in HNSCC patients identified by hypoxic FAZA-PET scanning

Description

Prospective phase II study aiming to improve the outcome in hypoxic resistent patients identified by FAZA-PET.

Inclusion:

Patients must fulfill the following:

Positive hypoxic FAZA-PET Scanning (as described in DAHANCA 24 - see citation) Stage III-IV, Squamous cell carcinoma of the larynx, pharynx or oral cavity (HPVneg (oropharynx) Indication for hyperfractionated accelerated radiotherapy with concommitant cis-platin and nimorazole

Study Design

Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Conditions

Locally Advanced Head and Neck Cancer

Intervention

HART-CN

Location

Department of Experimental Clinical Oncology, Aarhus University Hospital
Aarhus
Denmark
8000 C

Status

Not yet recruiting

Source

Danish Head and Neck Cancer Group

Results (where available)

View Results

Links

Published on BioPortfolio: 2016-11-30T15:45:38-0500

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