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Canola Oil Multi-center Intervention Trial II

2017-02-17 13:23:21 | BioPortfolio

Summary

Building on the findings from the investigators previous study, COMIT I, the purpose of the COMIT II study is to supplement the DEXA measurement of body composition with a supplementary DEXA measurement of visceral adipose tissue and to specifically target the impact of oleic acid consumption on body composition as the primary objective. COMIT II also will include analysis of fatty acid ethanolamines (FAEs) and their precursors to elucidate the mechanisms by which canola oil may be modifying body composition, measurement of endothelial function, inflammatory, adiposity and insulin sensitivity biomarkers, and genetic analyses.

Study Design

Conditions

Cardiovascular Disease

Intervention

Canola Oil, High oleic acid canola oil, Western diet oil combination

Location

Penn State University
University Park
Pennsylvania
United States
16802

Status

Completed

Source

Penn State University

Results (where available)

View Results

Links

Published on BioPortfolio: 2017-02-17T13:23:21-0500

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Medical and Biotech [MESH] Definitions

A plant species cultivated for the seed used as animal feed and as a source of canola cooking oil.

A colorless, syrupy, strongly acidic liquid that can form detergents with oleic acid.

A course of food intake that is high in FATS and low in CARBOHYDRATES. This diet provides sufficient PROTEINS for growth but insufficient amount of carbohydrates for the energy needs of the body. A ketogenic diet generates 80-90% of caloric requirements from fats and the remainder from proteins.

An unsaturated fatty acid that is the most widely distributed and abundant fatty acid in nature. It is used commercially in the preparation of oleates and lotions, and as a pharmaceutical solvent. (Stedman, 26th ed)

A diet typical of the Mediterranean region characterized by a pattern high in fruits and vegetables, cereals and bread, potatoes, poultry, beans, nuts, olive oil and fish while low in red meat and dairy and moderate in alcohol consumption.

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