Optimal Site of Administration for Continuous Wound Infusion After Cesarean Section
Summary
The purpose of this randomized double-blind study is to evaluate in which anatomical layer (AF versus BF) continuous wound infusion of local anesthetics combined with NSAIDs through a multiorifice catheter has the best effectiveness during the first 48 hours on postoperative pain intensity after elective cesarean delivery.
Study Design
Allocation: Randomized, Control: Active Control, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator, Outcomes Assessor), Primary Purpose: Treatment
Conditions
Cesarean Section
Intervention
Continuous wound infusion, Continuous wound
Location
Hôpital Cochin
Paris
France
75014
Status
Completed
Source
Association pour la Recherche et la Formation en Anesthésie Analgésie Réanimation
Results (where available)
Links
- Source: http://clinicaltrials.gov/show/NCT01160913
- Information obtained from ClinicalTrials.gov on July 15, 2010
Medical and Biotech [MESH] Definitions
Negative-pressure Wound Therapy
The application of a vacuum across the surface of a wound through a foam dressing cut to fit the wound. This removes wound exudates, reduces build-up of inflammatory mediators, and increases the flow of nutrients to the wound thus promoting healing.
Vaginal Birth After Cesarean
Delivery of an infant through the vagina in a female who has had a prior cesarean section.
Cesarean Section, Repeat
Extraction of the fetus by abdominal hysterotomy anytime following a previous cesarean.
Subgingival Curettage
Removal of degenerated and necrotic epithelium and underlying connective tissue of a periodontal pocket in an effort to convert a chronic ulcerated wound to an acute surgical wound, thereby insuring wound healing and attachment or epithelial adhesion, and shrinkage of the marginal gingiva. The term is sometimes used in connection with smoothing of a root surface or ROOT PLANING. (Jablonski; Illustrated Dictionary of Dentistry, 1982)
Surgical Wound Dehiscence
Pathologic process consisting of a partial or complete disruption of the layers of a surgical wound.
Clinical Trials
Wound complications after Cesarean section (C-section) are common in obese women. Approximately 25% of obese women having a C-section will have a wound complication. This research study i...
Appendectomy Versus no Appendectomy With Cesarean Section
Women having cesarean section will be divided into two groups - cesarean section alone or cesarean section with appendectomy. The purpose is to see if the appendectomy can be done without...
Diclofenac vs. Ropivacaine for Cesarean Section
A prospective, randomized, double blind study designed to investigate analgesic efficacy of wound infusion using diclofenac or ropivacaine following Cesarean section performed via a Pfanne...
Previous studies have demonstrated that patients who undergo surgery while they under general anesthesia have fewer wound infections if they receive higher concentrations of oxygen but thi...
The purpose of this study is to determine whether supplemental perioperative oxygen significantly decreases the incidence of post-Cesarean endometritis and wound infection among women who...
PubMed Articles
Wound infusion with local anesthetics is a nearly 100 years old proven and secure analgesic method. Recently special wound infusion catheters have become available which can be placed intraoperatively...
Background: Recent evidence suggests that locally delivered local anesthetics may exert tissue-damaging effects such as chondrolysis after intraarticular injection. Alteration of the inflammatory resp...
Wound dressings : Overview and classification.
Wound dressing and wound management are key words in current wound treatment. An unmanageably high number of products causes more confusion than clarification. Under continuous cost pressure in health...
Tramadol and levobupivacaine wound infiltration at Cesarean delivery for postoperative analgesia.
PURPOSE: The aim of the present study was to investigate whether levobupivacaine and tramadol wound infiltration decreases postoperative pain following Cesarean section and reduces the need for analge...
Omental packing with continuous suction drainage following abdominoperineal resection.
Background/Aims: Primary closure of the perineum along with drainage after abdominoperineal resection for lower rectal cancer is a widely accepted procedure but is associated with non-healing of the p...
