Gastric pH and Anthocyanin Absorption

2014-08-26 22:13:46 | BioPortfolio

Summary

Anthocyanins are phytonutrients that provide blue, purple and red colors to fruits and vegetables. The purpose of the study is to determine whether absorption of anthocyanins occurs in the acid pH of the stomach and to determine whether altering stomach pH by use of an over-the-counter medicine, Prilosec TM, alters absorption of anthocyanins from strawberries and blackberries.

Study Design

Allocation: Randomized, Control: Placebo Control, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Investigator, Outcomes Assessor)

Conditions

Anthocyanin Metabolism

Intervention

omeprazole, placebo

Location

USDA's Beltsville Human Nutrition Research Center
Beltsville
Maryland
United States
20705

Status

Recruiting

Source

United States Department of Agriculture

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-26T22:13:46-0400

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Medical and Biotech [MESH] Definitions

A cytochrome P-450 monooxygenase that can be induced by polycyclic aromatic xenobiotics in the liver of human and several animal species. This enzyme is of significant clinical interest due to the large number of drug interactions associated with its induction and its metabolism of THEOPHYLLINE. Caffeine is considered to be a model substrate for this enzyme. CYP1A2 activity can also be increased by environmental factors such as cigarette smoking, charbroiled meat, cruciferous vegetables, and a number of drugs including phenytoin, phenobarbital, and omeprazole.

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