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DMSO Efficacy in IC/PBS Patients During and After Treatment

2014-07-23 21:10:00 | BioPortfolio

Summary

The purpose of this study is to examine the efficacy of dimethylsulphoxide (DMSO) cocktail in patients with interstitial cystitis during the treatment period (12 weeks) and after it (at 6 weeks, 3, 6 and 12 month).

Description

The modern treatment of IC is a multi-modal treatment which includes behavioural treatment, physiotherapy of the pelvic floor musculature, oral medication (e.g. Amitryptiline) and intra-vesical instillation (e.g. DMSO, steroids, heparin). These treatments were found to be effective in a number of studies and are approved by the FDA. However, the optimal duration of intra-vesical instilation is not known.

All patients with IC (according to the international continence society criteria) will receive 12 weekly intra-vesical instillation of DMSO. All patients will fill an O'leary-Sant questionaire and a urination diary before treatment, after 3, 6, 9 and 12 treatments and at 6 weeks, 3, 6 and 12 month after the end to the treatment.

Study Design

Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Conditions

Cystitis, Interstitial

Intervention

DMSO cocktail

Location

Assaf Harofe Medical Center
Zeriffin
Israel
70300

Status

Recruiting

Source

Assaf-Harofeh Medical Center

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-07-23T21:10:00-0400

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