APPEndicitis and Laparoscopic Criteria; APPEL Study

11:58 EDT 25th April 2015 | BioPortfolio

Summary

A diagnostic laparoscopy is frequently used to confirm the diagnosis of appendicitis. However, laparoscopic criteria for determining appendicitis are not defined. If there is any doubt about the presence of an abnormal appendix, it is usually removed. However, an appendectomy of a negative appendix has a certain morbidity and for that reason it should be avoided. The purpose of this study is to establish laparoscopic criteria for the diagnosis appendicitis during diagnostic laparoscopy.

Description

The UMCG hospital protocol of suspicion of appendicitis includes a diagnostic laparoscopy. The laparoscopic inspection of the appendix is carried out according to a specific protocol. In case of appendicitis the appendix is removed laparoscopically, a normal appendix is not removed. The primary outcome of the study is: appendicitis according to pathologic examination following appendectomy, or appendicitis according to clinical follow-up in case the appendix is not removed.

The clinical diagnosis of appendicitis in the follow-up should be confirmed radiologic examination (ultrasound, CT-scan, MRI) or by a re-operation.

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Conditions

Appendicitis

Location

University Medical Center Groningen
Groningen
Netherlands
9700RB

Status

Recruiting

Source

University Medical Centre Groningen

Results (where available)

View Results

Links

Clinical Trials [37 Associated Clinical Trials listed on BioPortfolio]

Appendicitis With Medical Treatment

prospective study to collect data of patients with appendicitis, not receiving operation

Study of Conservative Versus Surgical Treatment of Appendicitis

The purpose of this study is to determine if antibiotic treatment of appendicitis is an option compared to surgery. The investigators' hypothesis is that a majority of patients with append...

Emergency Department CT Scanning for Appendicitis

The purpose of this study is to compare IV contrast only vs. IV and oral contrast Computed Tomography (CT) for the diagnosis of acute appendicitis in adult patients in our emergency depart...

Appendicectomy Versus Antibiotics in the Treatment of Uncomplicated Acute Appendicitis

Appendicectomy has been the treatment of acute appendicitis for over a hundred years. Appendicectomy, however, includes operative and postoperative risks despite being a "routine" operatio...

Morphine Analgesia in Patients With Acute Appendicitis

The purpose of the study is to evaluate morphine effect on pain reduction and diagnostic accuracy in patients admitted to emergency ward with the diagnosis of acute appendicitis.

PubMed Articles [96 Associated PubMed Articles listed on BioPortfolio]

Important CT findings for prediction of severe appendicitis: involvement of retroperitoneal space.

Determination of the severity of appendicitis and differentiation between complicated and uncomplicated appendicitis are clinically important. Severe appendicitis frequently affects extraperitoneal sp...

Impact of appendicitis during pregnancy: No delay in accurate diagnosis and treatment.

Acute appendicitis during pregnancy may be associated with serious maternal and/or fetal complications. To date, the optimal clinical approach to the management of pregnant women suspected of having a...

Prospective Validation of Alvarado Score and Pediatric Appendicitis Score for the Diagnosis of Acute Appendicitis in Children.

The purpose of this study was to compare the results of the Alvarado and Pediatric Appendicitis Score (PAS) scoring systems and to establish which one is more reliable in setting the diagnosis of acut...

Performance of CT Examinations in Children With Suspected Acute Appendicitis in the Community Setting: A Need for More Education.

Despite a recent focus on the preferential use of ultrasound over CT for pediatric appendicitis, most children transferred from community hospitals still undergo diagnostic CT scans. The purpose of th...

'Stump appendicitis': postappendectomy appendicitis.

Medical and Biotech [MESH] Definitions

Acute inflammation of the APPENDIX. Acute appendicitis is classified as simple, gangrenous, or perforated.

A genus of gram-negative, anaerobic bacteria in the family Desulfovibrionaceae. It was originally recovered from infections in patients with gangrenous and PERFORATED APPENDICITIS. It is also associated with ABSCESS; BACTEREMIA; and BILIARY TRACT sepsis.

Single or multiple areas of PUS due to bacterial infection within the hepatic parenchyma. It can be caused by a variety of BACTERIA, local or disseminated from infections elsewhere such as in APPENDICITIS; CHOLECYSTITIS; PERITONITIS; and after LIVER TRANSPLANTATION.

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