APPEndicitis and Laparoscopic Criteria; APPEL Study

2014-08-26 22:16:27 | BioPortfolio

Summary

A diagnostic laparoscopy is frequently used to confirm the diagnosis of appendicitis. However, laparoscopic criteria for determining appendicitis are not defined. If there is any doubt about the presence of an abnormal appendix, it is usually removed. However, an appendectomy of a negative appendix has a certain morbidity and for that reason it should be avoided. The purpose of this study is to establish laparoscopic criteria for the diagnosis appendicitis during diagnostic laparoscopy.

Description

The UMCG hospital protocol of suspicion of appendicitis includes a diagnostic laparoscopy. The laparoscopic inspection of the appendix is carried out according to a specific protocol. In case of appendicitis the appendix is removed laparoscopically, a normal appendix is not removed. The primary outcome of the study is: appendicitis according to pathologic examination following appendectomy, or appendicitis according to clinical follow-up in case the appendix is not removed.

The clinical diagnosis of appendicitis in the follow-up should be confirmed radiologic examination (ultrasound, CT-scan, MRI) or by a re-operation.

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Conditions

Appendicitis

Location

University Medical Center Groningen
Groningen
Netherlands
9700RB

Status

Recruiting

Source

University Medical Centre Groningen

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-26T22:16:27-0400

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Appendicectomy has been the treatment of acute appendicitis for over a hundred years. Appendicectomy, however, includes operative and postoperative risks despite being a "routine" operatio...

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PubMed Articles [105 Associated PubMed Articles listed on BioPortfolio]

Important CT findings for prediction of severe appendicitis: involvement of retroperitoneal space.

Determination of the severity of appendicitis and differentiation between complicated and uncomplicated appendicitis are clinically important. Severe appendicitis frequently affects extraperitoneal sp...

Value of Focused Appendicitis Ultrasound and Alvarado Score in Predicting Appendicitis in Children: Can We Reduce the Use of CT?

The purpose of this study was to evaluate the effectiveness of focused appendicitis ultrasound combined with Alvarado score to accurately identify appendicitis in children in whom it is suspected, the...

Impact of appendicitis during pregnancy: No delay in accurate diagnosis and treatment.

Acute appendicitis during pregnancy may be associated with serious maternal and/or fetal complications. To date, the optimal clinical approach to the management of pregnant women suspected of having a...

Prospective Validation of Alvarado Score and Pediatric Appendicitis Score for the Diagnosis of Acute Appendicitis in Children.

The purpose of this study was to compare the results of the Alvarado and Pediatric Appendicitis Score (PAS) scoring systems and to establish which one is more reliable in setting the diagnosis of acut...

Carcinoid Tumor of the Cecum Presenting with Acute Appendicitis: A Case Report.

Background: Acute appendicitis is the most common causeof acute abdomen. Carcinoid tumor of the appendix is a rareincidental finding that can present with the clinical pictureof acute appendicitis.

Medical and Biotech [MESH] Definitions

Acute inflammation of the APPENDIX. Acute appendicitis is classified as simple, gangrenous, or perforated.

A genus of gram-negative, anaerobic bacteria in the family Desulfovibrionaceae. It was originally recovered from infections in patients with gangrenous and PERFORATED APPENDICITIS. It is also associated with ABSCESS; BACTEREMIA; and BILIARY TRACT sepsis.

Single or multiple areas of PUS due to bacterial infection within the hepatic parenchyma. It can be caused by a variety of BACTERIA, local or disseminated from infections elsewhere such as in APPENDICITIS; CHOLECYSTITIS; PERITONITIS; and after LIVER TRANSPLANTATION.

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