Advertisement
Advertise here Publish your press releases here Sponsor BioPortfolio
Follow us on Twitter Sign up for daily news and research emails Contributors wanted

To Evaluate the Dose Response of 3 Doses of Euphorbia Prostrata in Patients With First and Second Degree Hemorrhoids

04:37 EDT 25th April 2014 | BioPortfolio

Summary

The purpose of this study is to determine the safe and efficacious dose of Euphorbia prostrata for control of per rectal bleeding in patients with first and second degree hemorrhoids.

Description

Hemorrhoidal disease is a common entity in the general population and in clinical practice. The basic pathological factor in hemorrhoids is the dilation of the anorectal venous plexuses. In the acute bleeding of internal hemorrhoids, one of the pathogenic processes implicated is the stagnation and stasis of blood in the vascular plexuses of the prolapsed anal cushions. Euphorbia prostrata extract is found to have antihemorrhoidal activity and is useful in ameliorating signs and symptoms associated with hemorrhoids.

Study Design

Allocation: Randomized, Control: Placebo Control, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment

Conditions

Hemorrhoids

Intervention

Euphorbia tablets, Euphorbia tablets, Euphorbia tablets, Placebo tablets

Location

Maulana Azad Medical College
New Delhi
Delhi
India
110002

Status

Recruiting

Source

Panacea Biotec Ltd

Results (where available)

View Results

Links

Medical and Biotech [MESH] Definitions

Tablets coated with material that delays release of the medication until after they leave the stomach. (Dorland, 28th ed)

A large plant genus of the family EUPHORBIACEAE, order Euphorbiales, subclass Rosidae. They have a milky sap and a female flower consisting of a single pistil, surrounded by numerous male flowers of one stamen each. Euphorbia hirta is rarely called milkweed but that name is normally used for ASCLEPIAS.

A disaccharide of GLUCOSE and GALACTOSE in human and cow milk. It is used in pharmacy for tablets, in medicine as a nutrient, and in industry.

Solid dosage forms, of varying weight, size, and shape, which may be molded or compressed, and which contain a medicinal substance in pure or diluted form. (Dorland, 28th ed)

Usually inert substances added to a prescription in order to provide suitable consistency to the dosage form. These include binders, matrix, base or diluent in pills, tablets, creams, salves, etc.

Clinical Trials [1013 Associated Clinical Trials listed on BioPortfolio]

Food Study of Lamotrigine Tablets 25 mg to Lamictal® Tablets 25 mg

The objective of this study was to investigate the bioequivalence of Mylan's lamotrigine 25 mg tablets to GlaxoSmithKline's (GSK) Lamictal® 25 mg tablets following a single, oral 50 mg (2...

Food Study of Letrozole Tablets 2.5 mg and Femara® Tablets 2.5 mg

The objective of this study was to investigate the bioequivalence of Mylan's letrozole 2.5 mg tablets to Novartis' Femara® 2.5 mg tablets following a single, oral 2.5 mg (1 x 2.5 mg) dose...

Food Study of Glimepiride Tablets 1 mg to Amaryl® Tablets 1 mg

The objective of this study was to investigate the bioequivalence of Mylan's glimepiride 1 mg tablets to Aventis Amaryl® 1 mg tablets following a single, oral 1 mg (1 x 1 mg) dose adminis...

Food Study of Pioglitazone HCl Tablets 45 mg to Actos® Tablets 45 mg

The objective of this study was to investigate the bioequivalence of Mylan pioglitazone HCl 45 mg tablets to Takeda Actos® 45 mg tablets following a single, oral 45 mg (1 x 45 mg) dose ad...

Food Study of Midodrine HCl Tablets 5 mg and ProAmatine® Tablets 5 mg

The objective of this study was to investigate the bioequivalence of Mylan's midodrine HCl 5 mg tablets to Roberts ProAmatine® 5 mg tablets following a single, oral 5 mg (1 x 5 mg) dose a...

PubMed Articles [811 Associated PubMed Articles listed on BioPortfolio]

The Preparation of Capsaicin-Chitosan Microspheres (CCMS) Enteric Coated Tablets.

This study aimed to research the preparation and content determination of capsaicin-chitosan microspheres (CCMS) enteric coated tablets. The core tablets were prepared with the method of wet granulati...

Effectiveness of binders in wet granulation: a comparison using model formulations of different tabletability.

Abstract Based on an analysis of model granulates and tablets, a comparison was made of the effectiveness of the binders PVP K30 PH, Cellulose HP-M 603, Lycatab DSH, Lycatab PGS, and L-HPC (type LH 11...

In-silico Simulation of Niacin Release from Lipid Tablets: Theoretical Predictions and Independent Experiments.

A mechanistically realistic mathematical model is presented allowing for the quantification of niacin release from lipid tablets, based on glyceryl dibehenate. The systems were prepared either by dire...

The efficacy and safety of Baoji Tablets for treating common cold with summer-heat and dampness syndrome: study protocol for a randomized controlled trial.

Despite the high incidence and the economic impact of the common cold, there are still no effective therapeutic options available. Although traditional Chinese medicine (TCM) is widely used in China t...

Efficiency of the iron supplementation programme for pregnant women in Jeneponto, Sulawesi, Indonesia.

An official iron supplementation programme for pregnant women in Jeneponto, South Sulawesi, Indonesia was assessed for efficiency. Data were collected in a cross-sectional study of 107 women in the se...

More From BioPortfolio on "To Evaluate the Dose Response of 3 Doses of Euphorbia Prostrata in Patients With First and Second Degree Hemorrhoids"

Search BioPortfolio:
Advertisement
Advertisement

Searches Linking to this Trial