Centralized Pan-South African Survey on the Undertreatment of Hypercholesterolaemia

Medical and Biotech [MESH] Definitions

Clinical Trials [ 17 Associated Clinical Trials listed on BioPortfolio]

Study of Asian Patients With Hypercholesterolaemia in the UK - Rosuvastatin 5mg Versus Atorvastatin 10mg

The purpose of this study is to compare the effectiveness and safety of rosuvastatin 5mg in lowering blood cholesterol, compared to one other medicine, atorvastatin 10mg in Asian patients...

A Study of the Safety and Efficacy of Patients With Familial Hypercholesterolaemia Taking Colesevelam as add-on Therapy to Their Existing Medication

This study is designed to assess whether colesevelam given as third line treatment added to a maximal tolerated and stable dose of a statin and ezetimibe is able to further decrease the le...

OLE Study to Evaluate Safety / Efficacy of ZD4522

The purpose of this study is to assess the long term safety of Crestor.

Carotid Atorvastatin Study in Hyperlipidemic Post-Menopausal Women

To evaluate the effect of atorvastatin 80 mg, versus placebo, given for 12 months on carotid intima-media thickness in postmenopausal women with moderate hypercholesterolemia.

Rosuvastatin Efficacy and Safety Evaluation in Hypercholesterolaemic Patients

This is a single-arm, phase IV, open-label, prospective, non interventional study to evaluate the efficacy, tolerability and safety of rosuvastatin administered for 24 weeks in approximate...

PubMed Articles [ 82 Associated PubMed Articles listed on BioPortfolio]

Treatment of familial hypercholesterolaemia in children and adolescents in the last three decades.

Background: This study evaluated the effectiveness of long-term intensive lipid-lowering therapy in children and adolescents with familial hypercholesterolaemia. Methods: The charts of 89 children and...

A double heterozygote for familial hypercholesterolaemia and familial defective apolipoprotein B-100.

BACKGROUND: Autosomal dominant hypercholesterolaemia is genetically heterogeneous, but most commonly ( approximately 93%) caused by mutations in low-density lipoprotein receptor (LDLR), where the dise...

Optimal BMI cut-off values for predicting diabetes, hypertension and hypercholesterolaemia in a multi-ethnic population.

OBJECTIVE: To determine the optimal cut-offs of BMI for Malaysian adults. DESIGN: Population-based, cross-sectional study. Receiver operating characteristic curves were used to determine the cut-off v...

Detection and care of familial hypercholesterolaemia in the community: is there a role for the pharmacist?

Familial hypercholesterolaemia (FH) is a dominantly inherited disorder present from birth that causes marked elevation in plasma cholesterol and premature coronary heart disease. It is estimated that...

Lipids: Targeting cascade screening in familial hypercholesterolaemia.