Clinical Validation of a Microfluidic Device for Isolation and Molecular Characterization of Circulating Tumor Cells
To evaluate the efficiency of a microdevice for circulating tumor cells isolation and to correlate the circulating titre with response and progression.
- Validate the clinical use of a mircofluidic device to capture circulating timor cells from a broad range of tumor types
- Characterize and identify these circulating tumor cells and demostrate cell viability with this capture method
- Apply this technology in clinically relevant settings and correlate to response to treatment and disease progression
- Elucidate predictive and pharmacodynamic biomarkers in the context of early phase trials of novel therapeutics
Observational Model: Cohort, Time Perspective: Prospective
National Cancer Centre
National Cancer Centre, Singapore
Results (where available)
- Source: http://clinicaltrials.gov/show/NCT01022723
- Information obtained from ClinicalTrials.gov on July 15, 2010
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Medical and Biotech [MESH] Definitions
The taking of a blood sample to determine its character as a whole, to identify levels of its component cells, chemicals, gases, or other constituents, to perform pathological examination, etc.
Skills and strategies, unrelated to the traits a test is intended to measure, that may increase test takers' scores -- may include the effects of coaching or experience in taking tests. (ERIC Thesaurus)
A cancer registry mandated under the National Cancer Act of 1971 to operate and maintain a population-based cancer reporting system, reporting periodically estimates of cancer incidence and mortality in the United States. The Surveillance, Epidemiology, and End Results (SEER) Program is a continuing project of the National Cancer Institute of the National Institutes of Health. Among its goals, in addition to assembling and reporting cancer statistics, are the monitoring of annual cancer incident trends and the promoting of studies designed to identify factors amenable to cancer control interventions. (From National Cancer Institute, NIH Publication No. 91-3074, October 1990)
Unlawful act of taking property.