Comparison of Refined and Crude Indigo Naturalis Ointment in Treating Psoriasis
Summary
The purpose of this study is to compare the efficacy and safety of refined oil extract ointment and crude ointment from indigo naturalis in the treatment of psoriatic vulgaris.
Study Design
Allocation: Randomized, Control: Active Control, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Treatment
Conditions
Psoriasis Vulgaris
Intervention
refined indigo naturalis ointment, crude indigo naturalis ointment
Location
Chang Gung Memorial Hospital
Keelung
Taiwan
204
Status
Enrolling by invitation
Source
Chang Gung Memorial Hospital
Results (where available)
Links
- Source: http://clinicaltrials.gov/show/NCT01022502
- Information obtained from ClinicalTrials.gov on July 15, 2010
Medical and Biotech [MESH] Definitions
Indigofera
A plant genus of the family FABACEAE. The common name of indigo also refers to Baptisia or Amorpha genera (FABACEAE).
Isatin
An indole-dione that is obtained by oxidation of indigo blue. It is a MONOAMINE OXIDASE INHIBITOR and high levels have been found in urine of PARKINSONISM patients.
Mineral Oil
A mixture of liquid hydrocarbons obtained from petroleum. It is used as laxative, lubricant, ointment base, and emollient.
Petrolatum
A colloidal system of semisolid hydrocarbons obtained from PETROLEUM. It is used as an ointment base, topical protectant, and lubricant.
Cetomacrogol
Non-ionic surfactant of the polyethylene glycol family. It is used as a solubilizer and emulsifying agent in foods, cosmetics, and pharmaceuticals, often as an ointment base, and also as a research tool.
Clinical Trials
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PubMed Articles
Indigo naturalis upregulates claudin-1 expression in human keratinocytes and psoriatic lesions.
Indigo naturalis is used in traditional Chinese medicine to treat various dermatoses. Our previous clinical studies showed that indigo naturalis is an effective treatment for psoriasis. Herein, the ca...
Indigo naturalis is used in traditional Chinese medicine to treat various skin disorders.
Reactions of indigo with anilines provide a simple route to indigo N,N'-diaryldiimines ("Nindigo"), a new binucleating ligand with two beta-diketiminate-type metal binding sites. Bis-palladium complex...
The two-compound ointment (Taclonex/Daivobet/Dovobet ointment) combining calcipotriene 50 microg/g and betamethasone 0.5 mg/g (as dipropionate) is very effective in the treatment of psoriasis vulgaris...
Despite the numerous studies of the famous indigo-based pigment Maya Blue, there are still many questions regarding the elucidation of its structure. Here, two-dimensional (2D) (1)H-(29)Si heteronucle...
