Metal Ion Release From an FDA-Approved Metal-on-Metal Total Hip Replacement Implant
Summary
This is a multi-center, randomized study to compare blood and urine cobalt, chromium, and titanium ion levels of a metal-on-metal articular bearing coupled with two different head sizes to that of a conventional metal-on-polyethylene bearing.
Study Design
Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Single Blind (Subject), Primary Purpose: Treatment
Conditions
Non-inflammatory Degenerative Joint Disease
Intervention
Total Hip Replacement
Location
Anderson Orthopaedic Research Institute
Alexandria
Virginia
United States
22306
Status
Active, not recruiting
Source
Anderson Orthopaedic Research Institute
Results (where available)
Links
- Source: http://clinicaltrials.gov/show/NCT00962351
- Information obtained from ClinicalTrials.gov on July 15, 2010
Medical and Biotech [MESH] Definitions
Arthroplasty, Replacement
Partial or total replacement of a joint.
Arthroplasty, Replacement, Finger
Partial or total replacement of one or more FINGERS, or a FINGER JOINT.
Arthroplasty, Replacement, Hip
Replacement of the hip joint.
Osteoarthritis
A progressive, degenerative joint disease, the most common form of arthritis, especially in older persons. The disease is thought to result not from the aging process but from biochemical changes and biomechanical stresses affecting articular cartilage. In the foreign literature it is often called osteoarthrosis deformans.
Enzyme Replacement Therapy
Therapeutic replacement or supplementation of defective or missing enzymes to alleviate the effects of the enzyme deficiency (e.g., GLUCOSYLCERAMIDASE replacement for GAUCHER DISEASE).
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