A Study of AL3583 Ophthalmic Solution 0.05%, 0.010% Versus AL38583 Vehicle for Dry Eye
Summary
The purpose of this study is to determine whether AL38583 Ophthalmic solution is effective for treatment of signs and symptoms of dry eye.
Study Design
Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment
Conditions
Dry Eye
Intervention
AL38583 Ophthalmic Solution 0.05%, AL38583 Ophthalmic Solution 0.10%, AL38583 Ophthalmic Solution Vehical
Location
Alcon Call Center for Trial Locations
Fort Worth
Texas
United States
76134
Status
Completed
Source
Alcon Research
Results (where available)
Links
- Source: http://clinicaltrials.gov/show/NCT00893139
- Information obtained from ClinicalTrials.gov on July 15, 2010
Medical and Biotech [MESH] Definitions
Ophthalmic Nerve
A sensory branch of the trigeminal (5th cranial) nerve. The ophthalmic nerve carries general afferents from the superficial division of the face including the eyeball, conjunctiva, upper eyelid, upper nose, nasal mucosa, and scalp.
Saline Solution, Hypertonic
Hypertonic sodium chloride solution. A solution having an osmotic pressure greater than that of physiologic salt solution (0.9 g NaCl in 100 ml purified water).
Tropicamide
One of the MUSCARINIC ANTAGONISTS with pharmacologic action similar to ATROPINE and used mainly as an ophthalmic parasympatholytic or mydriatic.
Ophthalmic Assistants
Persons academically trained to care for patients with eye diseases or structural defects of the eye, under the supervision of an ophthalmologist.
Triparanol
Antilipemic agent with high ophthalmic toxicity. According to Merck Index, 11th ed, the compound was withdrawn from the market in 1962 because of its association with the formation of irreversible cataracts.
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