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Curcumin in Pediatric Inflammatory Bowel Disease

2014-08-26 22:22:38 | BioPortfolio

Summary

This is a single center, open label forced dose titration study designed to determine the tolerability of curcumin in pediatric patients with inflammatory bowel disease (IBD). This study will provide initial tolerability and safety data in pediatric patients with IBD. Twenty patients with IBD in remission or with mild disease (score <34 on PUCAI or score <30 on the PCDAI) on sulfasalazine or mesalamine aged 8 to 18 years will be enrolled into this study. Each patient will participate in the study for nine weeks. From this study an appropriate dosage will be determined to proceed with a double blinded placebo controlled study.

Study Design

Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Conditions

Inflammatory Bowel Disease

Intervention

Curcumin

Location

Seattle Children's Hosptial
Seattle
Washington
United States
98105

Status

Completed

Source

Seattle Children's Hospital

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-26T22:22:38-0400

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Medical and Biotech [MESH] Definitions

An anti-inflammatory agent, structurally related to the SALICYLATES, which is active in INFLAMMATORY BOWEL DISEASE. It is considered to be the active moiety of SULPHASALAZINE. (From Martindale, The Extra Pharmacopoeia, 30th ed)

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