Eyelid Position Interdependence in Involutional Ptosis Patients Submitted to 10% Phenylephrine
Summary
The primary aim of this study is to quantify eyelid position changes in tested and opposite eyes in ptosis patients submitted to 1, 2 or 4 drops of 10% phenylephrine in one eye. The secondary objective is to correlate the eye dominance, severity and laterality of ptosis with eyelid position changes in these 3 groups.
Description
This is a prospective observational study conducted in involutional ptosis patients, which will be submitted to instillation of a single drop of 10% phenylephrine in one eye(Group 1), 2 drops (G2) or 4 drops ( G3).
Video camera will record the images of both eyes before and after drug application at 3, 10, 15 and 30 minutes. The images will be edited to analyze upper and lower lid height.
Study Design
Observational Model: Cohort, Time Perspective: Prospective
Conditions
Blepharoptosis
Location
Ophthalmology Dept. University of Sao Paulo General Hospital
Sao Paulo
Brazil
05403010
Status
Completed
Source
University of Sao Paulo
Results (where available)
Links
- Source: http://clinicaltrials.gov/show/NCT00864656
- Information obtained from ClinicalTrials.gov on July 15, 2010
Medical and Biotech [MESH] Definitions
Blepharoptosis
Drooping of the upper lid due to deficient development or paralysis of the levator palpebrae muscle.
Horner Syndrome
A syndrome associated with defective sympathetic innervation to one side of the face, including the eye. Clinical features include MIOSIS; mild BLEPHAROPTOSIS; and hemifacial ANHIDROSIS (decreased sweating)(see HYPOHIDROSIS). Lesions of the BRAIN STEM; cervical SPINAL CORD; first thoracic nerve root; apex of the LUNG; CAROTID ARTERY; CAVERNOUS SINUS; and apex of the ORBIT may cause this condition. (From Miller et al., Clinical Neuro-Ophthalmology, 4th ed, pp500-11)
Clinical Trials
None
PubMed Articles
Incomplete Gardner's syndrome with blepharoptosis as the first symptom.
Gardner's syndrome (GS) is an autosomal dominant form of polyposis characterized by the presence of multiple polyps in the colon together with osseous tumors and soft-tissue tumors, such as epidermoid...
Outcomes of levator resection in blepharoptosis patients with grafted corneas.
PURPOSE: To present the surgical results of, and postoperative complications after, resection of the levator aponeurosis as a treatment for aponeurotic blepharoptosis in patients with grafted corneas....
PURPOSE: To describe a modified surgical technique for blepharoptosis repair through a small orbital septum incision and minimal dissection, along with the results obtained in patients with coexisting...
Congenital Blepharoptosis Co-occurring With VATER Association.
VATER association is the tendency for 5 specific anomalies (vertebral and vascular anomalies [V], anal atresia [A], esophageal atresia and/or tracheoesophageal fistula [TE], and radial and renal anoma...
Re: "Silicone Rod Frontalis Suspension in Cases of High Risk Blepharoptosis"
