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RPS Adeno Detector HS for Diagnosing Adenoviral Conjunctivitis

2014-08-27 03:26:00 | BioPortfolio

Summary

The RPS Adeno Detector HS will be demonstrated to be more sensitive and specific than the RPS Adeno Detector™.

Description

To engage in a multi-center, prospective, masked clinical trial to investigate a non-invasive rapid pathogen screening test, the RPS Adeno Detector HS's ability to detect the presence of the adenovirus (ADV) antigen in cases of acute conjunctivitis by comparing it to both the RPS Adeno Detector™ and the polymerase chain reaction (PCR).

Currently, acute conjunctivitis is primarily a clinical diagnosis. Cultures are rarely performed due to the significant time delay in receiving results. Recently, the RPS Adeno Detector™ was both FDA cleared and CLIA waived. It is an antigen-based immunoassay that has the ability to detect the presence of ADV at the point of care. RPS Inc has made modifications to the sampling to pad and test strip to facilitate better antigen collection and release, respectively. It is believed that these changes will lead to better sensitivity, specificity, and ease of use of the test.

Study Design

Allocation: Non-Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Diagnostic

Conditions

Conjunctivitis

Intervention

Immunoassay

Location

Manatee Eye Clinic
Bradenton
Florida
United States
34208

Status

Completed

Source

Rapid Pathogen Screening

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:26:00-0400

Clinical Trials [67 Associated Clinical Trials listed on BioPortfolio]

ADenoVirus Initiative Study in Epidemiology in France

The objectives of this study is to assess the characteristics and frequency of adenovirus conjunctivitis in a population of male and female patients from one year of age who present signs ...

FST-100 in the Treatment of Acute Viral Conjunctivitis

This randomized, double masked, multi-center study is being conducted to support the safety and efficacy of FST-100 for the treatment of acute viral conjunctivitis. The study intends to sh...

A Study to Investigate the Safety and Efficacy of BOL-303224 in the Treatment of Bacterial Conjunctivitis

This is a study to investigate a novel drug candidate for the treatment of bacterial conjunctivitis.

Ketotifen Ophthalmic Solution With Emedastine in Patients With Seasonal Allergic Conjunctivitis

Medications available for the treatment of seasonal allergic conjunctivitis include antihistamines. These medicines block the release of histamine, a substance in the body that is released...

AL-15469A for the Treatment of Bacterial Conjunctivitis

The purpose of the study is to determine whether AL-15469A is safe and effective in the treatment of bacterial conjunctivitis.

PubMed Articles [266 Associated PubMed Articles listed on BioPortfolio]

Inter-Relationship between Rhinitis and Conjunctivitis in Allergic Rhinoconjunctivitis and Associated Risk Factors in Rural UK Children.

Allergic conjunctivitis (AC) is a common condition, especially in childhood. The extent to which it occurs concurrently with or independently from allergic rhinitis (AR) has not been well described.

Topical Application of Interleukin-28A Attenuates Allergic Conjunctivitis in an Ovalbumin-Induced Mouse Model.

Allergic conjunctivitis (AC) is an immunoglobulin E (IgE)-mediated and helper T cell 2 (Th2)--cell-mediated disease characterized by conjunctival eosinophilic infiltration. Previous study shows that I...

Topical Olopatadine in the Treatment of Allergic Conjunctivitis: A Systematic Review and Meta-analysis.

To assess the safety and efficacy of topical olopatadine versus placebo and other topical anti-allergic medications in treating allergic conjunctivitis.

Possible Mechanism of Action of the Antiallergic Effect of an Aqueous Extract of Heliotropium indicum L. in Ovalbumin-Induced Allergic Conjunctivitis.

Heliotropium indicum is used traditionally as a remedy for conjunctivitis in Ghana. This study therefore evaluated the antiallergic potential of an aqueous whole plant extract of Heliotropium indicum ...

Follicular Lymphoma Presenting Solely as Chronic Follicular Conjunctivitis.

Conjunctival lymphoma rarely can have atypical clinical presentations. The authors report a case of conjunctival follicular lymphoma that presented solely as bilateral chronic follicular conjunctiviti...

Medical and Biotech [MESH] Definitions

Conjunctivitis due to hypersensitivity to various allergens.

A highly contagious disease characterized by subconjunctival hemorrhage, sudden swelling of the eyelids and congestion, redness, and pain in the eye. Epidemic conjunctivitis caused by Enterovirus 70 (EV-70) was first described in Africa in 1969. It is caused also by Coxsackievirus A24 variant (CA24v). Epidemics by this organism have appeared most frequently in Asia.

An infection of the eyes characterized by the presence in conjunctival epithelial cells of inclusion bodies indistinguishable from those of trachoma. It is acquired by infants during birth and by adults from swimming pools. The etiological agent is CHLAMYDIA TRACHOMATIS whose natural habitat appears to be the genito-urinary tract. Inclusion conjunctivitis is a less severe disease than trachoma and usually clears up spontaneously.

An immunoenzyme test for the presence of drugs and other substances in urine and blood. The test uses enzyme linked antibodies that react only with the particular drug for which the sample is being tested.

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