Laparoscopic Cholecystectomy in Idiopathic Pancreatitis

22:19 EDT 29th March 2015 | BioPortfolio

Summary

The causes of acute pancreatitis in Finland are alcohol overuse (60%), cholecystolithiasis (20%) and idiopathic (i.e. etiology unknown)(20%). Acute pancreatitis may recur in over half of cases and may be fatal in severe cases in 30%. Majority of idiopathic pancreatitis are caused by microlithiasis in gall bladder. The purpose of this randomized study is to prevent recurrence of idiopathic pancreatitis by performing laparoscopic cholecystectomy compared to non-operative group in 2 years follow-up of patients.

Description

Etiologic investigations include serum amylase, lipase, triglyceride and calcium determination, as well as abdominal ultrasound scanning. Alcohol consumption is asked by using WHO audit test. After etiology of acute pancreatitis has been confirmed as idiopathic, 100 patients are randomized to laparoscopic cholecystectomy and 100 patients to follow-up of 2 years. Five to seven Finnish university and main central hospitals are participating the study.

Study Design

Allocation: Randomized, Control: Active Control, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Conditions

Idiopathic Pancreatitis

Intervention

Laparoscopic cholecystectomy

Location

Kuopio University Hospital
Kuopio
Finland
70211

Status

Recruiting

Source

Kuopio University Hospital

Results (where available)

View Results

Links

Clinical Trials [556 Associated Clinical Trials listed on BioPortfolio]

Early Versus Delayed Surgery for Gallstone Pancreatitis

While there exists consensus among surgeons that patients with gallstone pancreatitis should undergo cholecystectomy to prevent recurrence, the precise timing of laparoscopic cholecystecto...

SILS™ Port Laparoscopic Cholecystectomy Post Market Study

The objectives of this trial are: 1. to assess the feasibility and safety of performing SILS™ Port Laparoscopic Cholecystectomy 2. monitor and compare the outcomes of SI...

Prospective Evaluation of Laparoendoscopic Single Site Versus Laparoscopic Cholecystectomy

Laparoendoscopic single site cholecystectomy is associated with better cosmetic results and recovery compare to laparoscopic cholecystectomy.

Small-Incision Open Cholecystectomy or Laparoscopic Cholecystectomy for Gallbladder Disease

The trial compares minilaparotomy (small-incision) cholecystectomy with (key-hole) laparoscopic cholecystectomy by randomly allocating patients with gallbladder disease to two groups of su...

Robotic Assisted Versus Laparoscopic Cholecystectomy - Outcome and Cost Analyses of a Case-Matched Control Study

Case matched study on 50 consecutive patients undergoing robotic assisted cholecystectomy (Da Vinci Robot, Intuitive Surgical). These patients are matched 1:1 to 50 patients with conventio...

PubMed Articles [1949 Associated PubMed Articles listed on BioPortfolio]

Randomized, controlled trial comparing the effects of anesthesia with propofol, isoflurane, desflurane and sevoflurane on pain after laparoscopic cholecystectomy.

Pain is the primary complaint and the main reason for prolonged recovery after laparoscopic cholecystectomy. The authors hypothesized that patients undergoing laparoscopic cholecystectomy will have le...

Simplified laparoscopic cholecystectomy with two incisions.

Laparoscopic cholecystectomy has traditionally been performed with four incisions to insert four trocars, in a simple, efficient and safe way.

Cardiorespiratory evaluation in pre and post operative moments of laparoscopic cholecystectomy.

To analyze the changes in both respiratory function and cardiopulmonary exercise tests results in patients subjected to laparoscopic cholecystectomy.

Comparing the impact of intraperitoneal hydrocortisone with bupivacaine on postoperative pain after laparoscopic cholecystectomy.

Postoperative pain is a major complaint following laparoscopic cholecystectomy.

Laparoscopic Cholecystectomy in the Pediatric Population: A Single-center Experience.

We aimed to review our experience with laparoscopic cholecystectomy in the pediatric population to better understand the associated complications and outcomes.

Medical and Biotech [MESH] Definitions

Excision of the gallbladder through an abdominal incision using a laparoscope.

INFLAMMATION of the PANCREAS. Pancreatitis is classified as acute unless there are computed tomographic or endoscopic retrograde cholangiopancreatographic findings of CHRONIC PANCREATITIS (International Symposium on Acute Pancreatitis, Atlanta, 1992). The two most common forms of acute pancreatitis are ALCOHOLIC PANCREATITIS and gallstone pancreatitis.

Acute or chronic INFLAMMATION of the PANCREAS due to excessive ALCOHOL DRINKING. Alcoholic pancreatitis usually presents as an acute episode but it is a chronic progressive disease in alcoholics.

Surgical removal of the GALLBLADDER.

A group of interstitial lung diseases with no known etiology. There are several entities with varying patterns of inflammation and fibrosis. They are classified by their distinct clinical-radiological-pathological features and prognosis. They include IDIOPATHIC PULMONARY FIBROSIS; CRYPTOGENIC ORGANIZING PNEUMONIA; and others.

More From BioPortfolio on "Laparoscopic Cholecystectomy in Idiopathic Pancreatitis"

Search BioPortfolio:
Loading
Advertisement

Relevant Topic

Gastroenterology
Latest News Clinical Trials Research Drugs Reports Corporate
Diseases affecting the gastrointestinal tract, which includes the organs from mouth to anus, along the alimentary canal, are the focus of this specialty. Physicians practicing in this field of medicine are called gastroenterologists.  Gastroenterolo...

Advertisement