Domperidone in Refractory Gastroparesis
The primary objective of this study is to prescribe oral domperidone for patients with gastroparesis who have failed or suffered adverse effects from standard medical therapy.
Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
Yale Digestive Diseases 40 Temple St, Suite 1A
Results (where available)
- Source: http://clinicaltrials.gov/show/NCT00760461
- Information obtained from ClinicalTrials.gov on July 15, 2010
The purpose of this study is to examine the clinical response to domperidone in solid organ transplant recipients with gastroparesis.
The purpose of this study is to prescribe oral domperidone for subjects with gastrointestinal disorders who have failed or suffered adverse effects from standard medical treatment.
The purpose of this study is to make Domperidone available to patients with gastrointestinal disorders who have failed standard therapy and who might benefit from it.
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Medical and Biotech [MESH] Definitions
Chronic delayed gastric emptying. Gastroparesis may be caused by motor dysfunction or paralysis of STOMACH muscles or may be associated with other systemic diseases such as DIABETES MELLITUS.
A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
Abnormal distention of the STOMACH due to accumulation of gastric contents that may reach 10 to 15 liters. Gastric dilatation may be the result of GASTRIC OUTLET OBSTRUCTION; ILEUS; GASTROPARESIS; or denervation.