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Domperidone in Refractory Gastroparesis

12:09 EDT 24th April 2014 | BioPortfolio

Summary

The primary objective of this study is to prescribe oral domperidone for patients with gastroparesis who have failed or suffered adverse effects from standard medical therapy.

Study Design

Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Conditions

Gastroparesis

Intervention

Domperidone

Location

Yale Digestive Diseases 40 Temple St, Suite 1A
New Haven
Connecticut
United States
06510

Status

Recruiting

Source

Yale University

Results (where available)

View Results

Links

Medical and Biotech [MESH] Definitions

Chronic delayed gastric emptying. Gastroparesis may be caused by motor dysfunction or paralysis of STOMACH muscles or may be associated with other systemic diseases such as DIABETES MELLITUS.

A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.

Abnormal distention of the STOMACH due to accumulation of gastric contents that may reach 10 to 15 liters. Gastric dilatation may be the result of GASTRIC OUTLET OBSTRUCTION; ILEUS; GASTROPARESIS; or denervation.

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Domperidone for Relief of Gastrointestinal Disorders

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Unusual case of gastroparesis leading to severe gastromegaly with demyelinating disease as a rare cause.

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