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Domperidone in Refractory Gastroparesis

2010-07-15 17:00:00 | BioPortfolio

Summary

The primary objective of this study is to prescribe oral domperidone for patients with gastroparesis who have failed or suffered adverse effects from standard medical therapy.

Study Design

Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Conditions

Gastroparesis

Intervention

Domperidone

Location

Yale Digestive Diseases 40 Temple St, Suite 1A
New Haven
Connecticut
United States
06510

Status

Recruiting

Source

Yale University

Results (where available)

View Results

Links

Published on BioPortfolio: 2010-07-15T17:00:00-0400

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Domperidone for Refractory Gastrointestinal Disorders

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Domperidone for Relief of Gastrointestinal Disorders

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PubMed Articles [17 Associated PubMed Articles listed on BioPortfolio]

Exploration of the psychosocial issues associated with gastroparesis: A qualitative investigation.

To build on the understanding of how individuals experience gastroparesis, how gastroparesis impacts on their lives, and how they adapt to living with gastroparesis.

Gastroparesis in Noonan syndrome.

We present a case of a 26-year-old female patient with bloating, postprandial nausea and recurrent vomiting after solid food intake. A gastric emptying scintigraphy showed a delayed gastric emptying, ...

The Burdens, Concerns, and Quality of Life of Patients with Gastroparesis.

The impact of gastroparesis on patients from the patient's viewpoint is needed to better address treatment priorities. The aims of this study were to: (1) Delineate burdens and concerns of patients wi...

Synthesis of molecular imprinted polymers for selective extraction of domperidone from human serum using high performance liquid chromatography with fluorescence detection.

In this study a novel method is described for selective quantization of domperidone in biological matrices applying molecular imprinted polymers (MIPs) as a sample clean up procedure using high perfor...

Gastroparesis post-laparoscopic cholecystectomy in diabetic patients.

Impairment of gastric emptying is well recognized in patients with diabetes mellitus. The aim of this study was to investigate the influencing factors for gastroparesis syndrome development after lapa...

Medical and Biotech [MESH] Definitions

Chronic delayed gastric emptying. Gastroparesis may be caused by motor dysfunction or paralysis of STOMACH muscles or may be associated with other systemic diseases such as DIABETES MELLITUS.

A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.

Abnormal distention of the STOMACH due to accumulation of gastric contents that may reach 10 to 15 liters. Gastric dilatation may be the result of GASTRIC OUTLET OBSTRUCTION; ILEUS; GASTROPARESIS; or denervation.

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