Cognitive Behavioral Therapy for Trichotillomania
Summary
This study aims to develop a comprehensive Cognitive Behavioral Therapy protocol for adult patients with Trichotillomania that emphasizes relapse prevention and that addresses comorbid affective symptoms, as well. The study will compare the efficacy of CBT with a minimal attention control (MAC)condition. We hypothesize that outcome at post-treatment, 3-month, and 6-month follow-up will be better for the CBT vs. MAC condition including higher responder rates and greater reduction in hair pulling severity.
Description
The purpose of this study is to assess the efficacy of cognitive behavioral therapy for patients with trichotillomania.
Following entry into the study, subjects will be randomized into a cognitive behavioral therapy (CBT) or a minimized attention control (MAC) condition. Subjects will be assessed with the Acceptance and Action Questionnaire (AAQ), the Affective Regulation Rating (ARR), the Barratt Impulsivity Scale (BIS-11), Beck Depression Inventory (BDI), Beck Anxiety Inventory (BAI), Clinical Global Impressions Scale (CGI), the Difficulties in Emotion Regulation Scale (DERS), Hair Pulling Scale (HPS), Trichotillomania (TTM) Impact Scale, Psychiatric Institute Trichotillomania Scale (PITS), National Institute of Mental Health Trichotillomania Severity Scale(NIMH-TSS), the Generalized Expectancy for Negative Mood Regulation Scale (NMR), The Milwaukee Inventory for Subtypes of Trichotillomania- Adult Version (MIST-A), the Positive and Negative Affect Scale (PANAS), the Quality of Life Inventory (QOLI), the Readiness to Change Hairpulling Behavior (RCHPB), the Self-Esteem Scale (SES), the Skin Picking Scale (SPS) and the Scales of Psychological Well-Being (SPWB). Subject randomization to a treatment arm will be determined by a random number generator.
Subject change scores will be assessed for the above scales.
Study Design
Allocation: Randomized, Control: Active Control, Intervention Model: Parallel Assignment, Masking: Single Blind (Subject), Primary Purpose: Treatment
Conditions
Trichotillomania
Intervention
Cognitive Behavioral Therapy
Location
Massachusetts General Hospital
Boston
Massachusetts
United States
02114
Status
Recruiting
Source
Massachusetts General Hospital
Results (where available)
Links
- Source: http://clinicaltrials.gov/show/NCT00740909
- Information obtained from ClinicalTrials.gov on July 15, 2010
Medical and Biotech [MESH] Definitions
Cognitive Therapy
A direct form of psychotherapy based on the interpretation of situations (cognitive structure of experiences) that determine how an individual feels and behaves. It is based on the premise that cognition, the process of acquiring knowledge and forming beliefs, is a primary determinant of mood and behavior. The therapy uses behavioral and verbal techniques to identify and correct negative thinking that is at the root of the aberrant behavior.
Art Therapy
The use of art as an adjunctive therapy in the treatment of neurological, mental, or behavioral disorders.
Socioenvironmental Therapy
Therapy whose primary emphasis is on the physical and social structuring of the environment to promote interpersonal relationships which will be influential in reducing behavioral disturbances of patients.
Music Therapy
The use of music as an adjunctive therapy in the treatment of neurological, mental, or behavioral disorders.
Recreation Therapy
The enhancement of physical, cognitive, emotional and social skills so an individual may participate in chosen activities. Recreational modalities are used in designed intervention strategies, incorporating individual's interests to make the therapy process meaningful and relevant.
Clinical Trials
Cognitive Behavioral Treatment of Pediatric Trichotillomania
This study will compare the effectiveness of cognitive-behavior therapy (CBT) to a minimal attention control (AC) condition for treatment of pediatric trichotillomania (TTM).
Testing a New Therapy for Trichotillomania
This study will test the effectiveness of a new behavioral therapy for adults with trichotillomania (compulsive hair pulling).
N-Acetylcysteine for Pediatric Trichotillomania
Trichotillomania (hair pulling) has an estimated lifetime prevalence of 1-3%. Children with trichotillomania can experience significant impairment due to peer teasing, avoidance of activi...
Cognitive Behavioral Therapy Plus Drug Treatment for Obsessive Compulsive Disorder
This study will evaluate the effectiveness of two cognitive behavioral therapies (CBTs) in treating obsessive compulsive disorder (OCD) in patients who are taking medication but still have...
Methylphenidate in ADHD With Trichotillomania
This study will evaluate the safety and effectiveness of methylphenidate in treating attention deficit hyperactivity disorder (ADHD) in children with both ADHD and trichotillomania....
PubMed Articles
Trichotillomania and its treatment: a review and recommendations.
Trichotillomania (TTM) is characterized as an impulse control disorder in which individuals fail to resist urges to pull out their own hair, and is associated with significant functional impairment an...
Effects of acute modafinil on cognition in trichotillomania.
RATIONALE: Individuals with trichotillomania often report significant difficulty resisting the urges and drive to pull hair. OBJECTIVES: The aim of this study is to examine whether modafinil improves...
OBJECTIVE: This study determined whether adding cognitive-behavioral therapy to treatment for outpatients with schizophrenia would be more effective than the use of second-generation antipsychotics al...
Dronabinol, a cannabinoid agonist, reduces hair pulling in trichotillomania: a pilot study.
RATIONALE: Trichotillomania is characterized by repetitive pulling causing noticeable hair loss. Pharmacological treatment data for trichotillomania are limited. OBJECTIVE: Dronabinol appears to reduc...
DBT-enhanced habit reversal treatment for trichotillomania: 3-and 6-month follow-up results.
Background: Maintenance of gains with cognitive-behavioral treatment for trichotillomania (TTM) has historically been problematic. Methods: We conducted follow-up assessments 3 and 6 months after comp...
