Improvement of Insulin Resistance With Traditional Chinese Treatment in Patients With Type 2 Diabetes
Summary
The purpose of this study is to evaluate the efficacy of Traditional Chinese Treatment(TCT) on insulin sensitivity and other related factors in type 2 diabetes by using an double-blind, randomized, parallel control and prospective study This traditional compound Chinese herb preparation is referred to this study, with three kinds of plants: 50 mg of Coptis Chinensis, 30 mg of Astragalus mambranesceus and 120 mg of Lonicera Japonica, all of which are selected by The Chinese Academy of Medical Sciences among those traditionally considered effective and safe in the treatment of diabetes.
Patients enrolled were randomized into TCT group and placebo group administrated with TCT and placebo respectively. Glucose disposal rate (GDR), fasting plasma glucose (FPG), postprandial plasma glucose (PPG), HbA1C and other metabolic components were assessed at baseline and end point
Study Design
Allocation: Randomized, Control: Placebo Control, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double-Blind, Primary Purpose: Treatment
Conditions
Type 2 Diabetes
Intervention
Coptis Chinensis, Astragalus mambranesceus, Lonicera Japonica (Traditional Chinese Treatment), Placebo
Location
Shanghai Jiao Tong University School of Medicine
Shanghai
Shanghai
China
200025
Status
Completed
Source
Shanghai Jiao Tong University School of Medicine
Results (where available)
Links
- Source: http://clinicaltrials.gov/show/NCT00704236
- Information obtained from ClinicalTrials.gov on July 15, 2010
Medical and Biotech [MESH] Definitions
Astragalus Membranaceus
A plant species of the Astragalus genus which is source of Huang qi preparation used in TRADITIONAL CHINESE MEDICINE.
Medicine, Chinese Traditional
A system of traditional medicine which is based on the beliefs and practices of the Chinese culture.
Monascus
A genus in the family Monascaceae, order EUROTIALES. One species, Monascus purpureus, has multiple uses in traditional Chinese medicine (MEDICINE, CHINESE TRADITIONAL).
Ganoderma
A genus of fungi in the family Ganodermataceae, order POLYPORALES, containing a dimitic hyphal system. It causes a white rot, and is a wood decomposer. Ganoderma lucidum (REISHI) is used in traditional Chinese medicine (MEDICINE, CHINESE TRADITIONAL).
Cinnamomum Aromaticum
A plant species of the genus CINNAMOMUM that contains CINNAMATES and has been used in traditional Chinese medicine (DRUGS, CHINESE HERBAL).
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