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Repeated High-dose Inhaled Corticosteroids for Asthma

Summary

The purpose of this study is to to compare the effects of high-dose ICS vs. placebo in
adults with chronic stable asthma.

Study Design

Allocation: Randomized, Control: Placebo Control, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator), Primary Purpose: Treatment

Conditions

Asthma

Intervention

Placebo, Fluticasone

Location

The University of Chicago
Chicago
Illinois
United States
60637

Status

Recruiting

Source

University of Chicago

Results (where available)

View Results

MESH Definitions

Therapeutic Misconception

Misunderstanding among individuals, frequently research subjects, of scientific methods such as randomization and placebo controls.

Placebo Effect

An effect usually, but not necessarily, beneficial that is attributable to an expectation that the regimen will have an effect, i.e., the effect is due to the power of suggestion.

Asthma, Exercise-induced

Asthma attacks following a period of exercise. Usually the induced attack is short-lived and regresses spontaneously. The magnitude of postexertional airway obstruction is strongly influenced by the environment in which exercise is performed (i.e. inhalation of cold air during physical exertion markedly augments the severity of the airway obstruction; conversely, warm humid air blunts or abolishes it).

Anti-asthmatic Agents

Drugs that are used to treat asthma.

Orciprenaline

A beta-adrenergic agonist used in the treatment of asthma and bronchospasms.

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