TRial to Evaluate UltraSound in the Treatment of Tibial Fractures
Summary
The purpose of this study is to determine the effect of low-intensity, pulsed ultrasound on tibial fractures treated with intramedullary nailing.
Description
A randomized, placebo-treatment controlled, clinical trial to evaluate the safety and efficacy of low-intensity, pulsed ultrasound, applied to tibial fractures treated with intramedullary nailing.
Study Design
Allocation: Randomized, Control: Placebo Control, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment
Conditions
Tibial Fractures
Intervention
Exogen Bone Healing System
Location
Mobile
Alabama
United States
29605
Status
Recruiting
Source
Smith & Nephew, Inc.
Results (where available)
Links
- Source: http://clinicaltrials.gov/show/NCT00667849
- Information obtained from ClinicalTrials.gov on July 15, 2010
Medical and Biotech [MESH] Definitions
Femoral Neck Fractures
Fractures of the short, constricted portion of the thigh bone between the femur head and the trochanters. It excludes intertrochanteric fractures which are HIP FRACTURES.
Fractures, Compression
Crumbling or smashing of cancellous BONE by forces acting parallel to the long axis of bone. It is applied particularly to vertebral body fractures (SPINAL FRACTURES). (Blauvelt and Nelson, A Manual of Orthopedic Terminology, 1994, p4)
Fractures, Stress
Fractures due to the strain caused by repetitive exercise. They are thought to arise from a combination of MUSCLE FATIGUE and bone failure, and occur in situations where BONE REMODELING predominates over repair. The most common sites of stress fractures are the METATARSUS; FIBULA; TIBIA; and FEMORAL NECK.
Bony Callus
The bony deposit formed between and around the broken ends of BONE FRACTURES during normal healing.
Bone Density Conservation Agents
Agents that inhibit BONE RESORPTION and/or favor BONE MINERALIZATION and BONE REGENERATION. They are used to heal BONE FRACTURES and to treat METABOLIC BONE DISEASES.
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PubMed Articles
Segmental Tibial Fractures: An Infrequent but Demanding Injury.
BACKGROUND: Segmental tibial fractures are considered to be a special injury type associated with high complication rates. However, it is unclear whether healing of these fractures truly differs from...
Neuropeptide Y innervation during fracture healing and remodeling.
Background and purpose Autonomic neuropeptide Y (NPY) is involved in local bone remodeling via the central nervous system. However, the role of peripheral neuronal NPY in fracture healing is not known...
BACKGROUND: Nonunion of long bones in lower limbs is a common complication of orthopedic trauma that can be extremely debilitating. This retrospective study describes our experience using expandable i...
Tibial head fractures in the elderly.
In contrast to younger patients, tibial head fractures of the elderly usually result from minor trauma. In these patients, fractures of the tibial plateau are frequently seen and classified according...
The influence of compression on the healing of experimental tibial fractures.
PURPOSE: Experimental studies of the effects of various mechanical conditions and stimuli on bone healing have disclosed an improvement potential in bone fracture mineralization and biomechanical prop...
