Misoprostol With Intrauterine Device (IUD) Insertion
Summary
The purpose of this study is to see if using misoprostol (a medication that softens the cervix) before placing an IUD (intrauterine device) for contraception reduces pain in women who have never delivered a baby.
Description
We intend to conduct a randomized double blind study at Oregon Health and Science University and Planned Parenthood of the Columbia Willamette.
Subjects will be approached only after deciding to get an IUD. When the participants return for IUD placement, at 90 minutes prior to the procedure half will receive misoprostol and half will receive placebo. The subjects will be asked to rate their level of pain at specific points during the insertion. Providers will be asked to mark whether or not additional dilation was required as well as their perceived ease of IUD placement.
Study Design
Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Supportive Care
Conditions
Contraception
Intervention
Misoprostol, Magnesium Oxide
Location
Oregon Health & Science University
Portland
Oregon
United States
97239
Status
Active, not recruiting
Source
Oregon Health and Science University
Results (where available)
Links
- Source: http://clinicaltrials.gov/show/NCT00613366
- Information obtained from ClinicalTrials.gov on July 15, 2010
Medical and Biotech [MESH] Definitions
Magnesium Oxide
Magnesium oxide (MgO). An inorganic compound that occurs in nature as the mineral periclase. In aqueous media combines quickly with water to form magnesium hydroxide. It is used as an antacid and mild laxative and has many nonmedicinal uses.
Zinc Phosphate Cement
A material used for cementation of inlays, crowns, bridges, and orthodontic appliances and occasionally as a temporary restoration. It is prepared by mixing zinc oxide and magnesium oxide powders with a liquid consisting principally of phosphoric acid, water, and buffers. (From Bouchers' Clinical Dental Terminology, 3d ed)
Contraception, Barrier
Methods of contraception in which physical, chemical, or biological means are used to prevent the SPERM from reaching the fertilizable OVUM.
Magnesium Chloride
Magnesium chloride. An inorganic compound consisting of one magnesium and two chloride ions. The compound is used in medicine as a source of magnesium ions, which are essential for many cellular activities. It has also been used as a cathartic and in alloys.
Contraception Behavior
Behavior patterns of those practicing CONTRACEPTION.
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