Preoperative Chemoradiation Versus Short Term Radiation Alone With Delayed Surgery for Stage II and III Resectable Rectal Cancer
Summary
Trial compares two preoperative stage II and III rectal cancer treatment strategies: short term radiotherapy 5x5 Gy and delayed surgery after 6 weeks versus conventional chemoradiotherapy 50 Gy + 5Fu/Lv and surgery also after 6 weeks.
Study Design
Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
Conditions
Primary Rectal Cancer
Intervention
radiotherapy
Location
KMUH, surgery department
Kaunas
Lithuania
LT3000
Status
Recruiting
Source
Kaunas University of Medicine
Results (where available)
Links
- Source: http://clinicaltrials.gov/show/NCT00597311
- Information obtained from ClinicalTrials.gov on July 15, 2010
Medical and Biotech [MESH] Definitions
Radiotherapy, Adjuvant
Radiotherapy given to augment some other form of treatment such as surgery or chemotherapy. Adjuvant radiotherapy is commonly used in the therapy of cancer and can be administered before or after the primary treatment.
Rectal Neoplasms
Tumors or cancer of the RECTUM.
Radiotherapy Dosage
The total amount of radiation absorbed by tissues as a result of radiotherapy.
Radiotherapy, High-energy
Radiotherapy using high-energy (megavolt or higher) ionizing radiation. Types of radiation include gamma rays, produced by a radioisotope within a teletherapy unit; x-rays, electrons, protons, alpha particles (helium ions) and heavy charged ions, produced by particle acceleration; and neutrons and pi-mesons (pions), produced as secondary particles following bombardment of a target with a primary particle.
Radiation Oncology
A subspecialty of medical oncology and radiology concerned with the radiotherapy of cancer.
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