Advertisement

Topics

Evaluation of the Wear of Vitamin E Treated Polyethylene Components in Primary THA Using RSA

2015-05-03 15:25:44 | BioPortfolio

Summary

The specific aim of this proposed study is to conduct a prospective RSA clinical study at Massachusetts General Hospital involving 50 patients receiving primary total hip replacements. All patients will receive the vitamin E treated polyethylene acetabular inserts. Short-term femoral head penetration and long-term steady state wear of the polyethylene will be measured using both RSA and Martell analysis techniques. Stability of the acetabular and femoral components will be measured in all patients using RSA analysis. The stability of the cemented femoral stems will be compared to the stability of the cementless femoral components as well as to historic data in the literature. In addition, all patients will complete a self-administered questionnaire to assess the clinical outcome of the surgery and patient satisfaction.

Study Design

Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Conditions

Osteoarthritis of Hip

Intervention

Hip replacement

Location

Massachusetts General Hospital
Boston
Massachusetts
United States
02114

Status

Recruiting

Source

Massachusetts General Hospital

Results (where available)

View Results

Links

Published on BioPortfolio: 2015-05-03T15:25:44-0400

Clinical Trials [1009 Associated Clinical Trials listed on BioPortfolio]

Chondromodulating Effect of Diacerein in Osteoarthritis of the Hip

We carried out a 3 years, randomized, double-blind, placebo-controlled, multicenter clinical trial in patients with hip osteoarthritis in order to: - evaluate the ability of diacerein,...

A Multicenter Study to Evaluate the ConforMIS iTotal® (CR) Knee Replacement System Versus Off-the-Shelf Replacement

Patients will be randomized to either ConforMIS iTotal Knee Replacement or Off the Shelf knee replacement. The patient will conduct functional testing and answer questionnaires. Th...

Randomized Controlled Study Comparing CFP and Corail Stem

80 patients eligible for a total hip replacement (THR) mainly due to primary osteoarthritis were recruited from our waiting list. The patients were randomized to either CFP or Corail stem,...

Role of Bone in Knee Osteoarthritis (OA)

The purpose of the study is to investigate the density, architecture, and perfusion of bone marrow lesions (BMLs) in knee osteoarthritis. We will perform MRI's and QCT's on subjects prior ...

Study of a Steroid Delivery System for Pain Relief Treatment in Patients With Knee Osteoarthritis

The purpose of this study is to determine whether a longer duration, controlled, sustained release dexamethasone delivery system would be more effective in helping patients with osteoarthr...

PubMed Articles [1970 Associated PubMed Articles listed on BioPortfolio]

The causal role of smoking on the risk of hip or knee replacement due to primary osteoarthritis: a Mendelian randomisation analysis of the HUNT Study.

Smoking has been associated with a reduced risk of hip and knee osteoarthritis and subsequent joint replacement. The aim of the present study was to assess whether the observed association is likely t...

Lifetime risk of primary total hip replacement surgery for osteoarthritis from 2003-2013: A multi-national analysis using national registry data.

To compare the lifetime risk of total hip replacement surgery (THR) for osteoarthritis (OA) between countries, and over time.

Determinants of knee replacement in subjects with a history of arthroscopy: data from the osteoarthritis initiative.

To investigate the risk and determinants of knee replacement (KR) in subjects with or at risk of osteoarthritis (OA) and a history of arthroscopy.

Projecting Lifetime Risk of Symptomatic Knee Osteoarthritis and Total Knee Replacement in Individuals Sustaining a Complete Anterior Cruciate Ligament Tear in Early Adulthood.

To estimate the lifetime risk of knee osteoarthritis (OA) and total knee replacement (TKR) in persons sustaining ACL tear by age 25.

Validity and Responsiveness of the Knee injury and Osteoarthritis Outcome Score (KOOS): A Comparative Study among Total Knee Replacement Patients.

To evaluate validity and responsiveness of the Knee injury and Osteoarthritis Outcome Score (KOOS) in relation to other patient-reported outcome measures before and after total knee replacement (TKR).

Medical and Biotech [MESH] Definitions

Therapeutic replacement or supplementation of defective or missing enzymes to alleviate the effects of the enzyme deficiency (e.g., GLUCOSYLCERAMIDASE replacement for GAUCHER DISEASE).

Partial or total replacement of a joint.

Replacement of the hip joint.

Partial or total replacement of one or more FINGERS, or a FINGER JOINT.

Organic compounds containing the -CO-NH2 radical. Amides are derived from acids by replacement of -OH by -NH2 or from ammonia by the replacement of H by an acyl group. (From Grant & Hackh's Chemical Dictionary, 5th ed)

More From BioPortfolio on "Evaluation of the Wear of Vitamin E Treated Polyethylene Components in Primary THA Using RSA"

Quick Search
Advertisement
 

Searches Linking to this Trial