HBV-specific T-cell Immunity in Individuals With HIV/HBV Co-infection
Summary
The trial will randomise HIV/HBV co-infected individuals to different HBV-active antiretroviral therapy treatment regimens.
Description
Longitudinal study of circulating and intra-hepatic HBV-specific T-cell immunity in the setting of a randomised, controlled, international, multi-centre outpatient trial. The trial will randomise HIV/HBV co-infected individuals to different HBV-active antiretroviral therapy treatment regimens.
Study population: Patients with HIV/HBV co-infection who are naive to HIV/HBV therapy, have detectable HBV viremia and are willing to start antiretroviral therapy.
Study Design
Observational Model: Case-Only, Time Perspective: Prospective
Conditions
HIV
Location
Hiv-Nat
Bangkok
Thailand
Status
Completed
Source
The HIV Netherlands Australia Thailand Research Collaboration
Results (where available)
Links
- Source: http://clinicaltrials.gov/show/NCT00476723
- Information obtained from ClinicalTrials.gov on July 15, 2010
Medical and Biotech [MESH] Definitions
Calcimycin
An ionophorous, polyether antibiotic from Streptomyces chartreusensis. It binds and transports cations across membranes and uncouples oxidative phosphorylation while inhibiting ATPase of rat liver mitochondria. The substance is used mostly as a biochemical tool to study the role of divalent cations in various biological systems.
Temefos
An organothiophosphate insecticide.
Abattoirs
Places where animals are slaughtered and dressed for market.
Abbreviations As Topic
Shortened forms of written words or phrases used for brevity.
Abdomen
That portion of the body that lies between the THORAX and the PELVIS.
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