Gene Function

Gene Therapy

p53 Gene Therapy rDNA Introgen

p53 Gene Therapy rDNA Shenzhen

Prothrombin 20210 Gene Mutation

In epigenomics, location is everything: Researchers exploit gene position to test 'histone code'

In a novel use of gene knockout technology, researchers tested the same gene inserted into 90 different locations in a yeast chromosome -- and discovered that while the inserted gene never altered its...

Gene therapy medicinal products: the first gene therapy product has been approved – where does the future lie?

Is gene therapy close to broad clinical application? Following negative headlines at the end of the 1990s, gene therapy had almost disappeared from the public radar to become an issue almost exclusive...

Elusive gene that causes a form of blindness from birth dlscovered

Researchers have isolated an elusive human gene that causes a common form of Leber congenital amaurosis (LCA), a relatively rare but devastating form of early-onset blindness. The new LCA gene is call...

Gene ohne Vorlage

Viele Gene sind komplette Neuerfindungen und nicht nur abgewandelte Kopien älterer Gene

SYMPHONY, an information-theoretic method for gene–gene and gene–environment interaction analysis of disease syndromes

In epigenomics, location is everything

In a novel use of gene knockout technology, researchers at the University of California, San Diego School of Medicine tested the same gene inserted into 90 different locations in a yeast chromosome â€...

In Gene Expression, Length Matters

Gene ends communicate Human genomes harbour thousands of genes, each of which gives rise to proteins when it is active. But which inherent features of a gene determine its activity? Postdoctoral Scho...

Sensing gene therapy

Sensory disorders can have a profound effect on health and quality of life—but gene therapy may be coming to the rescue. Gene therapy’s success in treating  blindness disorders –many are in lat...

A high frequency of the Cystic Fibrosis 2184insA mutation in Western Ukraine: Genotype-phenotype correlations, relevance for newborn screening and genetic testing.

We present the first comprehensive report on the distribution and genotype-phenotype correlations of CF-causing mutations in Western Ukraine (former Galicia). The 2184insA mutation was identified in 1...

GEIRA: gene-environment and gene-gene interaction research application.

The GEIRA (Gene-Environment and Gene-Gene Interaction Research Application) algorithm and subsequent program is dedicated to genome-wide gene-environment and gene-gene interaction analysis. It impleme...

Effect of FAK, DLC-1 gene expression on OVCAR-3 proliferation.

The study investigates the effect of FAK, DLC-1 on OVCAR-3 proliferation. FAK gene siRNA vector recombinant plasmid was constructed using RNA interference technique. FAK gene-transfected OVCAR-3 cells...

Radiochemotherapy of hepatocarcinoma via lentivirus-mediated transfer of human sodium iodide symporter gene and herpes simplex virus thymidine kinase gene.

Herpes simplex virus thymidine kinase (HSV-TK) gene/ganciclovir (GCV) system has been widely used as a traditional gene therapy modality, and the sodium/iodide symporter gene (NIS) has been found to b...

Microfluidic approaches for gene delivery and gene therapy.

Recent advances in microfluidics have created new and exciting prospects for gene delivery and therapy. The micro-scaled environment within microfluidic systems enables precise control and optimizatio...