Search Results for "Acute Myeloid Leukemia"
Original Source: The role of peptide and DNA vaccines in myeloid leukemia immunotherapy.
ABSTRACT: While chemotherapy and targeted therapy are successful in inducing the remission of myeloid leukemia as acute myeloid leukemia (AML) and chronic myeloid leukemia (CML), the disease remains largely incurable. This observation is likely due to the drug resistance of leukemic cells, which are responsible for disease relapse. Myeloid leukemia vaccines may most likely be beneficial for eradicating minimal residual disease after treatment with chemotherapy or targeted therapy. Several targeted immunothe...
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Acute leukemia occurs when a hematopoietic stem cell undergoes malignant transformation into a primitive, undifferentiated cell with abnormal longevity. These lymphocytes (acute lymphocytic leukemia...
Acute myelocytic leukemia is a life-threatening disease in which the neutrophil, basophil, eosinophil, and monocyte precursors become cancerous and rapidly replace normal cells in the bone marrow....
Oncohist™ exhibits the same properties as the body's own histone H1.3 molecules and has consequently low immunogenicity and antigenicity. Extensive data have shown that Oncohist molecules...
Acute Lymphocytic Leukemia ALL
Acute lymphocytic leukemia (ALL) is a life-threatening disease in which the cells that normally develop into lymphocytes become cancerous and rapidly replace normal cells in the bone marrow. ALL acc...
Chronic leukemia is a long term increase of abnormal white blood cells. It can be classed as myelogenous or lymphocytic leukemia. For more information see the Leukemia pages Add the Leukemia New...
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Iclusig Approved for CML and ALL
The U.S. Food and Drug Administration (FDA) has approved Iclusig™ (ponatinib) to treat adults with chronic myeloid leukemia (CML) and Philadelphia chromosome-positive acute lymphoblastic leukemia (P...
Smart drug improves survival in older patients with acute myeloid leukemia
(Cardiff University) Acute myeloid leukemia accounts for around a third of all leukemias diagnosed in the UK. A new study has found Acute Myeloid Leukemia patients given a new type of "smart drug" in...
Possible new acute leukemia marker, treatment target identified
A study has identified microRNA-155 as a new independent prognostic marker and treatment target in patients with acute myeloid leukemia that has normal-looking chromosomes under the microscope (that i...
Study identifies possible new acute leukemia marker, treatment target
(Ohio State University Medical Center) A study has identified microRNA-155 as a new independent prognostic marker and treatment target in patients with acute myeloid leukemia that has normal-looking c...
News From The Journal Of Clinical Investigation: July 16, 2012
ONCOLOGY A new target in acute myeloid leukemia Acute myeloid leukemia, a common leukemia in adults, is characterized by aberrant proliferation of cancerous bone marrow cells. Activating mutations i...
Risk for Acute Myeloid Leukemia Linked to Chemotherapy
The risk of developing treatment-related acute myeloid leukemia needs to be weighed against the benefits of chemotherapy Medscape Medical News
Two University of Colorado Cancer Center studies show that the protein receptor Mer is overexpressed in many leukemias, and that inhibition of this Mer receptor results in the death of leukemia cells...
A new target in acute myeloid leukemia
Acute myeloid leukemia, a common leukemia in adults, is characterized by aberrant proliferation of cancerous bone marrow cells. Activating mutations in a protein receptor known as FLT3 receptor are am...
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The role of peptide and DNA vaccines in myeloid leukemia immunotherapy.
ABSTRACT: While chemotherapy and targeted therapy are successful in inducing the remission of myeloid leukemia as acute myeloid leukemia (AML) and chronic myeloid leukemia (CML), the disease remains l...
Prognostic factors and outcomes of adult patients with acute myeloid leukemia after first relapse.
BackgroundAlthough patients with acute myeloid leukemia who were treated with conventional chemotherapy still have a substantial risk of relapse, the prognostic factors and optimal treatments after re...
Our knowledge about acute promyelocytic leukemia (APL) patients is mainly based on data from clinical trials, whereas population-based information is scarce. We studied APL patients diagnosed between...
