Vitamin E Deficiency

Frank vitamin E deficiency is rare and overt deficiency symptoms have not been found in healthy people who obtain little vitamin E from their diets. Premature babies of very low birth weight (<1,...

IgA Deficiency

Deficiency

Vitamin B12 Deficiency

Iron deficiency

Vitamin B12 Deficiency Prevalent Among Refugees

New research from the University of Adelaide has discovered a high prevalence of vitamin B12 deficiency among refugees, prompting calls for refugees to be routinely screened for the problem soon after...

Vitamin D deficiency may contribute to alcohol-related muscular weakness

Myopathy refers to a muscular disease in which muscle fibers do not function, resulting in muscular weakness and wasting. Vitamin D deficiency is a well-recognized cause of myopathy, and excessive dri...

Vitamin D Deficiency An Increased Risk In Obesity

Obesity can lead to a lack of vitamin D circulating in the body, according to a study led by the UCL Institute of Child Health (ICH). Efforts to tackle obesity should thus also help to reduce levels o...

Diagnosis and treatment of growth hormone deficiency in adults

Adult growth hormone (GH) deficiency is now recognized as a distinct if nonspecific syndrome with considerable adverse health consequences. This Review outlines the physiological regulation and nonsta...

A Hollywood Ending For Northwest Biotherapeutics? It All Depends On Phase III

ByRichard Richter:A neighbor of mine recently participated in a focus group translating a questionnaire designed for patients with growth hormone (GH) deficiency. The yes/no questions ranged from "I f...

Mild vitamin B12 deficiency associated with accelerated cognitive decline

A study conducted at the Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University associates mild vitamin B-12 deficiency with accelerated cognitive decline in men and women, begin...

Prevalence and Predictors of Vitamin D Deficiency in Adults

Black and Asian patients may be at risk of vitamin D deficiency. Endocrine Practice

New Vitamin D Deficiency Campaign Launched By RCPCH

Increased knowledge among health care professionals, readily available and inexpensive vitamin D supplements, more public awareness, and fortification of foods are several steps required to address th...

Clinical features of severe acquired ADAMTS13 deficiency in thrombotic thrombocytopenic purpura: the Korean TTP registry experience.

The clinical significance of ADAMTS13 activity for response to treatment, mortality rate, recurrence, and prognosis is unclear. Therefore, we investigated the characteristics of severe ADAMTS13 defici...

Ten patient stories illustrating the extraordinarily diverse clinical features of patients with thrombotic thrombocytopenic purpura and severe ADAMTS13 deficiency.

Patients with thrombotic thrombocytopenic purpura (TTP) and severe ADAMTS13 deficiency are often considered to have typical clinical features. However, our experience is that there is extraordinary di...

How I treat patients with thrombotic thrombocytopenic purpura - 2010.

Thrombotic thrombocytopenic purpura (TTP) is the common name for adults with microangiopathic hemolytic anemia, thrombocytopenia, with or without neurologic or renal abnormalities, and without another...

Thrombospondin-1 and ADAMTS13 competitively bind to VWF A2 and A3 domains in vitro.

INTRODUCTION: ADAMTS13 (a disintegrin-like and metalloprotease with thrombospondin type 1 repeat motif. 13) is the major metalloprotease for VWF degradation. ADAMTS13 deficiency causes the accumulatio...

Usefulness of antithrombin deficiency phenotypes for risk assessment of venous thromboembolism: type I deficiency as a strong risk factor for venous thromboembolism.

Inherited antithrombin deficiency, an established risk factor for venous thromboembolism (VTE), can be classified into type I (quantitative deficiency) or type II (qualitative deficiency). In the pres...