Search Results for "Amitriptyline Ketamine"
Original Source: Randomised clinical trial: the effects of amitriptyline on drinking capacity and symptoms in patients with functional dyspepsia, a double-blind placebo-controlled study.
Background Functional dyspepsia is one of the most prevalent (15-40%) functional gastrointestinal disorders. Antidepressants such as amitriptyline are often used in these patients, but clinical studies are currently lacking. Aim To evaluate the effect of 8 weeks of treatment with amitriptyline on drinking capacity, symptoms evoked by a standardised drink test (primary endpoint) and clinical symptoms (secondary endpoint). Methods Patients meeting the Rome III criteria for functional dyspepsia (FD)...
Matching Channels
Matching News
EpiCept moving forward with pain, say Edison analysts
US drug developer EpiCept's (Nasdaq; EPCT) investment case is centered on finding a development partner for AmiKet (amitriptyline 4%, ketamine 2% cream), a product for chemotherapy-induced peripheral...
Amitriptyline Shows Promise as Local Dental Anesthetic
A controlled trial of the antidepressant amitriptyline applied in a mucoadhesive tablet suggests the drug has promise as a topical anesthetic in dentistry. Medscape Medical News
For the opioid-tolerant patient, ketamine could be the key to managing acute postoperative pain. Medscape Nurses
Researchers studying ketamine as suicide prevention drug
(Medical Xpress)—University of Alabama at Birmingham (UAB) researchers think ketamine, an anesthesia medication in use since the 1970s, might be a valuable tool in treating severe depression and red...
How ketamine vanquishes depression within hours
Many chronically depressed and treatment-resistant patients experience immediate relief from symptoms after taking small amounts of the drug ketamine. For [...]
Researchers look at therapeutic benefits of ketamine
The largest trial into the use of Electroconvulsive Therapy (ECT) in the UK in more than 30 years will look into how the use of the Class C drug ketamine might reduce the side effects of ECT for those...
Ketamine for Bipolar Depression
Evidence is accumulating for ketamine's acute antidepressant effect in biopolar as well as unipolar depression, but this short-term study did not address the risk for induction of mania and cycling....
How ketamine defeats chronic depression
Many chronically depressed and treatment-resistant patients experience immediate relief from symptoms after taking small amounts of the drug ketamine. For a decade, scientists have been trying to expl...
Matching PubMed Articles
Effects of co-administration of amitriptyline and fluoxetine on inhibitory avoidance in mice.
We have previously observed that, while the impairing effects of amitriptyline on inhibitory avoidance in mice are consistently observed, those of acute fluoxetine are negligible. Two experiments were...
PURPOSE: We investigated the heat pain threshold (HPT) and temporal summation threshold (TST) before and after target-controlled infusion (TCI) of ketamine with an effect-site concentration (Ce) of 30...
A tricyclic anti-depressant, amitriptyline, is a highly prescribed drug for cancer patients for mood elevation but there are limited studies about the interaction of amitriptyline with glutathione S-t...
We have demonstrated previously that the ketamine-induced discriminative stimulus effect is likely to reflect the phencyclidine-like psychotomimetic effects. Therefore, the present study was designed...
Effect of amitriptyline on glycinergic transmission in rat medullary dorsal horn neurons.
Amitriptyline, a representative tricyclic antidepressant, has been widely used for the treatment of neuropathic pain, such as post-herpetic and trigeminal neuralgia. In the present study, we investiga...
