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Search Results for "Andrographis Cedars Sinai Trial"

08:55 EDT 24th May 2013 | BioPortfolio

Original Source: Randomised clinical trial: herbal extract HMPL-004 in active ulcerative colitis - a double-blind comparison with sustained release mesalazine.

Background  Andrographis paniculata is an herbal mixture used to treat inflammatory diseases. An extract of the herb, HMPL-004, inhibits TNF-α and IL-1β, and prevents colitis in animal models. Aim  To determine the efficacy and safety of HMPL-004 in patients with mild-to-moderate ulcerative colitis. Methods  A randomised, double-blind, multicentre, 8-week parallel group study was conducted using HMPL-004 1200 mg/day compared with 4500 mg/day of slow release mesalazine (mesalamine) granules in pa...

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