Volume depletion

Na depletion and excess

Anti Infective Peptides

Anti-viral peptides are used to treat infections such as HIV and AIDS, influenza incl. H5N1 strains, hepatitis C virus infections (HCV). Anti-bacterial peptides are used to treat infectiou...

Anti-Inhibitor Coagulant Baxter

Anti-Inhibitor Coagulant Nabi

[Comment] Anti-interleukin-2 receptor alpha for multiple sclerosis?

In The Lancet, Ralf Gold and colleagues report the results of their 52-week, randomised, placebo-controlled, dose-ranging, phase 2 study of daclizumab high-yield process (HYP)—a humanised monoclonal...

Glucocorticoid-induced TNFR Family-Related Receptor Ligand (GITRL) Antibodies for Diagnosis and Treatment of Immune System Disorders

This technology provides novel antibodies and methods for diagnostics and treatment of disorders arising from dysregulation of the immune system using antibodies directed against glucocorticoid-induce...

Depletion of DNA Precursors May Trigger Cellular Senescence

The tumor suppressing mechanism known as oncogene-induce cellular senescence results from DNA damage that might be triggered by depletion...

US Food Security Threatened By Groundwater Depletion In Semiarid Regions Of Texas And California

The nation's food supply may be vulnerable to rapid groundwater depletion from irrigated agriculture, according to a new study by researchers at The University of Texas at Austin and elsewhere. The st...

Copper Depletion May Slow Breast Cancer Relapse

In high-risk patients, copper depletion decreased the number of cells linked to metastatic angiogenesis. Medscape Medical News

Induction of M2-like macrophages in recipient NOD-scid mice by allogeneic donor CD4+CD25+ regulatory T cells

Groundwater Depletion Threatens U.S. Food Security

The nation’s food supply may be vulnerable to rapid groundwater depletion from irrigated agriculture, according to a new study by [...]

Inhibition of activation induced CD154 on CD4+ CD25− cells: a valid surrogate for human Treg suppressor function

Regulatory T Cell Properties of Chicken CD4+CD25+ Cells.

Chicken CD4(+)CD25(+) cells were characterized for mammalian regulatory T cells' suppressive and cytokine production properties. Anti-chicken CD25 mAb was produced in mice and conjugated with a fluore...

The suppressive effect of CD25+Treg cells on Th1 differentiation requires cell-cell contact partially via TGF-β production.

CD4+CD25+Foxp3+ regulatory T cells (CD25+Treg cells) play a central role in the maintenance of peripheral self-tolerance and immune homeostasis. Previous study showed that CD25+Treg cells suppressed t...

Identification, frequency, activation and function of CD4+ CD25(high)FoxP3+ regulatory T cells in children with juvenile idiopathic arthritis.

The aim of the study was to test the frequency of CD4+ CD25(high)FoxP3 regulatory T cells in JIA patients and to assess their activation status and functional activity. The study involved 12 children...

Decreased Levels of Circulating CD4+CD25+Foxp3+ Regulatory T Cells in Patients with Primary Antiphospholipid Syndrome.

INTRODUCTION: CD4(+)CD25(+)Foxp3(+) regulatory T (Treg) cell dysfunction has been documented in various autoimmune disorders, but not in antiphospholipid syndrome (APS) so far. METHODS: In this cross-...

Depletion of CD4+CD25+Foxp3+ regulatory T cells with anti-CD25 antibody may exacerbate the 1,3-β-glucan-induced lung inflammatory response in mice.

1,3-β-Glucan was a major cell wall component of fungus. The existing studies showed that 1,3-β-glucan exposure could induce lung inflammation that involved both Th1 and Th2 cytokines. Regulatory T c...