O2 therapy

Immediate therapy

Neoadjuvant therapy

Neoadjuvant therapy is the administration of therapeutic agents before the main treatment. One example is neoadjuvant hormone therapy prior to radical radiotherapy for adenocarcinoma of the prostate...

Oxygen therapy

Gene Therapy

Targeted therapies for systemic sclerosis

In the era of targeted therapy, patients with rheumatic diseases have seen real results. But what about those with systemic sclerosis—where is the long-awaited antifibrotic drug? Disparate aspects o...

Researchers foresee new therapies and diagnostics for deadly fibrotic diseases

A team of scientists has developed a playbook for ending the devastating impact of fibrotic diseases of the liver, lung, kidney, and other organs, which are responsible for as many as 45 percent of al...

Hope For New Therapies And Diagnostics For Deadly Fibrotic Diseases

A team of scientists has developed a playbook for ending the devastating impact of fibrotic diseases of the liver, lung, kidney, and other organs, which are responsible for as many as 45 percent of al...

USPTO grants patent for galactomannan-based carbohydrate galectin inhibitor compounds

Galectin Therapeutics, the leading developer of therapeutics that target galectin proteins to treat fibrosis and cancer, today announced that it has received a notice of allowance from the U.S. Patent...

Gene therapy medicinal products: the first gene therapy product has been approved – where does the future lie?

Is gene therapy close to broad clinical application? Following negative headlines at the end of the 1990s, gene therapy had almost disappeared from the public radar to become an issue almost exclusive...

Medicare Reimbursement for Outpatient Therapy

Today I review Medicare’s approach for paying for outpatient therapy visits. The content draws largely from CMS and MedPAC sources. What is outpatient therapy Outpatient therapy includes physica...

Intermittent hormone therapy for prostate cancer inferior to continuous therapy

(University of Michigan Health System) An international randomized study finds intermittent androgen-deprivation therapy has some quality-of-life benefits, but overall survival times don't measure up...

Elite Physical Therapy Hosts Senator

PROVIDENCE, RI -- U.S. Sen. Sheldon Whitehouse (D-RI) visited Elite Physical Therapy in Providence Jan. 7 to share his views on the current Medicare issues relating to the field of physical therapy an...

Antifibrotic Activity of Sorafenib in Experimental Hepatic Fibrosis: Refinement of Inhibitory Targets, Dosing, and Window of Efficacy In Vivo.

BACKGROUND: Sorafenib, which is approved for treatment of HCC, has also shown promising antifibrotic activity, and therefore refinement of its dosing requirements and window of efficacy are important...

Antifibrotic constituents of Alnus firma on hepatic stellate cells.

Suppression of hepatic stellate cell (HSC) growth and activation have been proposed as therapeutic strategies for the treatment and prevention of liver fibrosis. In the course of screening antifibroti...

Suramin attenuates dystrophin-deficient cardiomyopathy in the mdx mouse model of Duchenne muscular dystrophy.

Introduction: To evaluate the effects of suramin, an antifibrotic agent, on the cardiac function and remodeling in the mdx mice. Methods: mdx mice (8 months old) received intraperitoneal injections of...

Tyrosine Kinase Inhibitors in the Treatment of Systemic Sclerosis: From Animal Models to Clinical Trials.

Efficient antifibrotic therapies are not available for patients with systemic sclerosis (SSc). This review summarizes the current preclinical and clinical evidence for imatinib and related tyrosine ki...

Current status of novel antifibrotic therapies in patients with chronic liver disease.

Fibrosis accumulation is a dynamic process resulting from a wound-healing response to acute or chronic liver injury of all causes. The cascade starts with hepatocyte necrosis and apoptosis, which inst...