Sickle Cell Disease

Cholesterol

Cholesterol is a waxy steroid metabolite found in the cell membranes and transported in the blood plasma. It is an important structural component of mammalian cell membranes, where it is establishes...

Serum urate level

Spleen Disorders

Located under your left lung, beneath the diaphragm, the spleen has two functions; lymphocyte production (which takes place in the white pulp) and filtration of the blood by phagocytes to remove mic...

Lowering the serum urate level

Sickle cell disease, sickle cell trait are not the same

(HealthDay)—Both sickle cell disease and the condition known as sickle cell trait are genetic blood diseases: You're born with one or the other because of the genes inherited from your parents. Beyo...

Gaps in Care Found for Sickle Cell Disease Patients

MONDAY, Dec. 10 (HealthDay News) -- There are major gaps in medical care for sickle cell disease patients as they move from childhood to adulthood, new research finds. Sickle cell disease is an inher...

Management of an acute painful sickle cell episode in hospital: summary of NICE guidance

Sickle cell disease comprises a group of lifelong, inherited conditions of haemoglobin formation. Although the sickle gene is found in all ethnic groups, most people affected with sickle cell disease....

Sickle cell disease: Physics explains how sickling cells make people sick

Researchers have identified the physical forces in red blood cells and blood vessels underlying the painful symptoms of sickle cell disease. Their experiment, the first to answer a scientific question...

Sickle Cell Disease Wiped Out In Selected Patients By 'Half-Match' Bone Marrow Transplants

In a preliminary clinical trial, investigators at Johns Hopkins have shown that even partially-matched bone marrow transplants can eliminate sickle cell disease in some patients, ridding them of painf...

For Patients With Sickle Cell Disease, New Studies Reveal Critical Insights To Improve Care

Research unveiling key gaps in continuity of care for sickle cell patients transitioning from pediatric to adult care were during the 54th Annual Meeting of the American Society of Hematology (ASH). S...

Bone marrow transplants hold promise for sickle cell patients

Research shows that even partially matched bone marrow transplants are able to eliminate sickle cell disease in some patients with sickle cell anemia.

Wheeze predicts sickle cell disease crisis

Wheezing is a significant indicator for morbidity in patients with sickle cell disease, US researchers believe.

Reproductive Decisions in People With Sickle Cell Disease or Sickle Cell Trait.

In the context of an inherited condition such as sickle cell disease (SCD), it is critical to understand how people with SCD or carriers (sickle cell trait [SCT]) face the challenges of making informe...

Race and social attitudes about sickle cell disease.

Objective. Sickle cell disease is perhaps the most racialized condition in the history of modern medicine, yet very little research has focused on how racial perceptions influence social attitudes abo...

Preoperative Exchange Transfusion for Sickle Cell Disease Patients Undergoing Open-Heart Surgery: An Exception to the Rule.

Abstract Preoperative exchange transfusion is a routine practice in patients with sickle cell disease having elevated sickle cell hemoglobin levels (>40%) undergoing open-heart surgery on cardiopulmon...

Neonatal Screening of Sickle Cell Anemia: A Preliminary Report.

OBJECTIVE: To evaluate feasibility of systematic neonatal screening for sickle cell disease in Chhattisgarh. METHODS:...

A simple, rapid, low-cost diagnostic test for sickle cell disease.

This communication describes a very simple, rapid and inexpensive point-of-care diagnostic test for sickle cell disease (SCD) that can conclusively differentiate between blood samples from normal heal...