Sickle Cell Disease

Parkinson's Disease

Parkinson's is a progressive neurological condition, affecting one person in every 500, 95% of which are over 40. It is caused by degeneration of more than 70% of the substantia nigra, which dep...

Amyotrophic Lateral Sclerosis ALS Lou Gehrig's disease

Amyotrophic lateral sclerosis (ALS, also called Lou Gehrig's disease) is a rapidly progressing, motor neuron disease characterized by the gradual degeneration and death of motor neurons. When muscles...

Spleen Disorders

Located under your left lung, beneath the diaphragm, the spleen has two functions; lymphocyte production (which takes place in the white pulp) and filtration of the blood by phagocytes to remove mic...

CombiCult

CombiCult® is an award winning, combinatorial screening technology that allows scientists to discover new and improved stem cell differentiation protocols. How Combicult® works A short o...

Sickle cell disease, sickle cell trait are not the same

(HealthDay)—Both sickle cell disease and the condition known as sickle cell trait are genetic blood diseases: You're born with one or the other because of the genes inherited from your parents. Beyo...

Gaps in Care Found for Sickle Cell Disease Patients

MONDAY, Dec. 10 (HealthDay News) -- There are major gaps in medical care for sickle cell disease patients as they move from childhood to adulthood, new research finds. Sickle cell disease is an inher...

Management of an acute painful sickle cell episode in hospital: summary of NICE guidance

Sickle cell disease comprises a group of lifelong, inherited conditions of haemoglobin formation. Although the sickle gene is found in all ethnic groups, most people affected with sickle cell disease....

Potential gene therapy approach to sickle cell disease highlighted at American Society of Hematology

(Boston Children's Hospital) Researchers at Dana-Farber/Children's Hospital Cancer Center have taken the first preliminary steps toward developing a form of gene therapy for sickle cell disease.

Sickle cell disease: Physics explains how sickling cells make people sick

Researchers have identified the physical forces in red blood cells and blood vessels underlying the painful symptoms of sickle cell disease. Their experiment, the first to answer a scientific question...

Researchers highlight potential gene therapy approach to sickle cell disease

Researchers at Dana-Farber/Children's Hospital Cancer Center (DF/CHCC) have taken the first preliminary steps toward developing a form of gene therapy for sickle cell disease. In an abstract presented...

Potential Gene Therapy Approach To Sickle Cell Disease

Researchers at Dana-Farber/Children's Hospital Cancer Center (DF/CHCC) have taken the first preliminary steps toward developing a form of gene therapy for sickle cell disease. In an abstract presented...

Sickle Cell Disease Wiped Out In Selected Patients By 'Half-Match' Bone Marrow Transplants

In a preliminary clinical trial, investigators at Johns Hopkins have shown that even partially-matched bone marrow transplants can eliminate sickle cell disease in some patients, ridding them of painf...

Reproductive Decisions in People With Sickle Cell Disease or Sickle Cell Trait.

In the context of an inherited condition such as sickle cell disease (SCD), it is critical to understand how people with SCD or carriers (sickle cell trait [SCT]) face the challenges of making informe...

Gene therapy for sickle cell disease.

BACKGROUND: Sickle cell disease encompasses a group of genetic disorders characterized by the presence of at least one hemoglobin S (Hb S) allele, and a second abnormal allele that could allow abnorma...

Race and social attitudes about sickle cell disease.

Objective. Sickle cell disease is perhaps the most racialized condition in the history of modern medicine, yet very little research has focused on how racial perceptions influence social attitudes abo...

Preoperative Exchange Transfusion for Sickle Cell Disease Patients Undergoing Open-Heart Surgery: An Exception to the Rule.

Abstract Preoperative exchange transfusion is a routine practice in patients with sickle cell disease having elevated sickle cell hemoglobin levels (>40%) undergoing open-heart surgery on cardiopulmon...

Neonatal Screening of Sickle Cell Anemia: A Preliminary Report.

OBJECTIVE: To evaluate feasibility of systematic neonatal screening for sickle cell disease in Chhattisgarh. METHODS:...