Search Results for "Articular Capsule Drug Delivery"
Original Source: Intra-Articular Microparticles for Drug Delivery to the TMJ.
This study describes he in vivo biocompatibility of intra-articular poly(DL-lactic-co-glycolic acid) (PLGA) microparticle (MP) formulations in the rat temporomandibular joint (TMJ). To our knowledge, this is the first intra-articular microparticle-based drug delivery system for the TMJ. The impact of PLGA MP concentration on rat TMJ function was quantified via computerized meal pattern analysis; in this non-invasive technique, previously validated markers of TMJ pain or nociception (specifically, meal durat...
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Drug Delivery - news, views, blogs
Drug delivery is the method or process of administering a pharmaceutical compound to achieve a therapeutic effect in humans or animals. Drug delivery technologies are patent protected formulat...
PolyXen® is an enabling technology for protein drug delivery. It uses the natural polymer polysialic acid (PSA) to prolong the active life and improve the stability of therapeutic peptides...
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Research Into Articular Cartilage Provides Insight Into Osteoarthritis
A researcher at The Feinstein Institute for Medical Research has discovered additional mechanical properties of articular cartilage, a protective cartilage on the ends of bones that wears down over ti...
Repairing articular cartilage defects with an injectable gel engineered with gene modified BMSCs
(Society for Experimental Biology and Medicine) Tissue engineering combined with gene therapy technology has the potential to manage the repair of defective articular cartilage. In this study, through...
Extra-articular Manifestations in Spondyloarthritis
What are the extra-articular manifestations associated with spondyloarthritis, and how are they best managed? Therapeutic Advances in Musculoskeletal Disease
Type: Original PaperThis study set out to develop a novel and stable nanoemulsion formulation of natural vitamin E with increased oral bioavailability. The natural vitamin E nanoemulsion was prepared...
Tissue engineering combined with gene therapy can manage repair of defective articular cartilage
Researchers at Micro Orthopaedics, Zhongnan Hospital of Wuhan University, led by Dr. Ai-xi Yu, have suggested that articular cartilage defects can be repaired by a novel thermo-sensitive injectable hy...
Injectable Gel Engineered With Gene Modified BMSCs To Repair Articular Cartilage Defects
Researchers at Micro Orthopaedics, Zhongnan Hospital of Wuhan University, led by Dr. Ai-xi Yu, have suggested that articular cartilage defects can be repaired by a novel thermo-sensitive injectable hy...
Flexion ramps funding to drive alliances for intra-articular osteoarthritis drugs
Flexion Therapeutics lined up $20 million in a Series B funding round to help the company generate mid-stage data that could make the Woburn, Massachusetts-based firm's arthritis drugs delivered via i...
Intermittent Motion Capsule Filler
The AlterNova capsule filler is specially designed to be flexible so that growing nutritional products companies can easily increase production or change product forms and sizes.Read more about Interm...
Matching PubMed Articles
Intra-Articular Microparticles for Drug Delivery to the TMJ.
This study describes he in vivo biocompatibility of intra-articular poly(DL-lactic-co-glycolic acid) (PLGA) microparticle (MP) formulations in the rat temporomandibular joint (TMJ). To our knowledge,...
A novel plug-controlled colon-specific pulsatile capsule with tablet of curcumin-loaded SMEDDS.
This study developed and evaluated a colon-specific pulsatile capsule with tablet of self-microemulsifying drug delivery system (SMEDDS). This system is based on an impermeable capsule containing a ra...
Capsule shells adulterated with tadalafil.
Following a health complaint a food supplement was brought in for analysis on the suspicion of being adulterated with a synthetic drug substance. When the capsule content did not show evidence of adul...
PURPOSE: Conventional bioavailability testing of dosage forms based on plasma concentration-time graphs of two products in a two-period, crossover-design, is not applicable to topical treatment of int...
Oral administration of celecoxib (Clx), which is the traditional treatment for osteoarthritis (OA), is accompanied by a high risk for cardiovascular events, while intra-articular injection of hyaluron...
