Search Results for "Asp015k Rheumatoid Arthritis"
Matching Channels
Rheumatoid arthritis (RA) is a chronic systemic disease characterized by progressive joint deformity and joint destruction driven by synovial inflammation and hyperplasia in which cytokines play cen...
Arthritis - publications, news, reports
Arthritis is by definition the inflammation of one or more joints, characterized by swelling, pain, warmth, redness and diminished range of joint movement (Oxford Medical Dictionary). There are ma...
Technical Background Tumor necrosis factor (TNF) is a substance made by your body's immune system. People with inflammatory diseases such as rheumatoid arthritis, plaque psoriasis, psoriatic a...
Matching News
Janssen Biotech and Astellas agree to license small molecule ASP015K
Janssen Biotech has entered into a license agreement with Astellas Pharma for the worldwide development and commercialization, except in Japan, of ASP015K, an oral, small molecule Janus Kinase inhibit...
Extra Pounds Linked to Rheumatoid Arthritis Risk in Women
SATURDAY, Nov. 10 -- Overweight and obese women are at increased risk for rheumatoid arthritis, a new study suggests. Rheumatoid arthritis is an autoimmune disease that causes pain, swelling, stiffnes...
Rheumatoid arthritis patients can get gout too, study finds
Refuting a belief long held by many physicians, a Mayo Clinic study found that rheumatoid arthritis patients also can get gout. The research is among several studies Mayo Clinic is presenting at the A...
Women Who Smoke May Have Higher Risk for Rheumatoid Arthritis
FRIDAY, April 26 (HealthDay News) -- Smokers and former smokers are at increased risk for rheumatoid arthritis, a new study says. Researchers analyzed data collected from 34,000 women, aged 54 to 89,...
Similar Names, Very Different Conditions
Rheumatoid arthritis and osteoarthritis have little in common. By Kari Bohlke, ScD At first glance the word arthritis seems straightforward: it means “joint inflammation.” The reality, however, is...
Gene's role in rheumatoid arthritis uncovered: Findings pave way for new treatments
Research sheds new light on why certain people are more likely to suffer from rheumatoid arthritis -- paving the way to explore new treatments for both arthritis and other autoimmune diseases.
Plasma biomarker predicts rheumatoid arthritis onset
Healthy individuals with high levels of immunoglobulin G rheumatoid factor have a significantly increased risk for developing rheumatoid arthritis, suggests population-based research published in the...
Gene's Role In Rheumatoid Arthritis Revealed; Discovery May Extend To Other Autoimmune Diseases
University of Michigan research sheds new light on why certain people are more likely to suffer from rheumatoid arthritis - paving the way to explore new treatments for both arthritis and other autoim...
Matching PubMed Articles
The L55M polymorphism of paraoxonase-1 is a risk factor for rheumatoid arthritis.
araoxonase-1 (PON1) is a high-density lipoprotein-associated enzyme that exhibits antioxidant and antiatherogenic activities. We examined a possible association between T172A (L55M) and T(-107)C polym...
Methotrexate alone or in combination with other agents is the standard treatment for moderate-to-severe rheumatoid arthritis. As biological agents are expensive, they are not usually used until methot...
To assess the efficacy and safety of R788 (fostamatinib disodium), an inhibitor of spleen tyrosine kinase (Syk), in patients with active rheumatoid arthritis (RA) that did not respond to biologic ther...
Rheumatoid Arthritis-Interstitial Lung Disease-Associated Mortality.
RATIONALE: Mortality rates from rheumatoid arthritis-associated interstitial lung disease are largely unknown. OBJECTIVES: We sought to determine mortality rates from rheumatoid arthritis-associated i...
Rheumatoid arthritis is an autoimmune disorder which involves inflammation of the synovial tissue, leading to synovial proliferation, bone erosion and ultimately joint disability. It is a complex diso...
