Sickle Cell Disease

Stem Cells

Stem cells can be found in all multicellular organisms and are characterized by the ability to renew themselves through mitotic cell division and differentiate into a diverse range of specialized ce...

The Asymptomatic Patient With Abnormal Laboratory Test Results

Spleen Disorders

Located under your left lung, beneath the diaphragm, the spleen has two functions; lymphocyte production (which takes place in the white pulp) and filtration of the blood by phagocytes to remove mic...

Squamous Cell Carcinoma

Squamous cell carcinoma (SCC) is a carcinomatous cancer occurring in many different organs, including the skin, lips, mouth, esophagus, urinary bladder, prostate, lungs, vagina, and cervix. It is a...

Sickle cell disease, sickle cell trait are not the same

(HealthDay)—Both sickle cell disease and the condition known as sickle cell trait are genetic blood diseases: You're born with one or the other because of the genes inherited from your parents. Beyo...

Sickle cell anemia: Maps and newborn estimates released

In 2010 around 300,000 babies were born with sickle cell anemia, a serious blood disorder which can be fatal if untreated, and 5.5 million newborns inherited the sickle cell gene, a new study suggests...

Management of an acute painful sickle cell episode in hospital: summary of NICE guidance

Sickle cell disease comprises a group of lifelong, inherited conditions of haemoglobin formation. Although the sickle gene is found in all ethnic groups, most people affected with sickle cell disease....

Gaps in Care Found for Sickle Cell Disease Patients

MONDAY, Dec. 10 (HealthDay News) -- There are major gaps in medical care for sickle cell disease patients as they move from childhood to adulthood, new research finds. Sickle cell disease is an inher...

Sickle cell disease trial completes phase 3 patient enrollment

Emmaus Medical, Inc., a specialty pharmaceutical and regenerative medicine company, today announced the completion of patient enrollment for its phase 3 clinical trial to study L-glutamine as a treatm...

Mapping the global burden of sickle cell anaemia

The first rigorous study to assess the global burden of sickle cell anaemia in recent times is reported today in the Lancet, giving an up-to-date view of the distribution of the disease. Accurate esti...

Bone marrow transplants hold promise for sickle cell patients

Research shows that even partially matched bone marrow transplants are able to eliminate sickle cell disease in some patients with sickle cell anemia.

Chicago woman cured of sickle cell disease

A Chicago woman is the first Midwest patient to receive a successful stem cell transplant to cure her sickle cell disease without chemotherapy in preparation for the transplant.

Reproductive Decisions in People With Sickle Cell Disease or Sickle Cell Trait.

In the context of an inherited condition such as sickle cell disease (SCD), it is critical to understand how people with SCD or carriers (sickle cell trait [SCT]) face the challenges of making informe...

Preoperative Exchange Transfusion for Sickle Cell Disease Patients Undergoing Open-Heart Surgery: An Exception to the Rule.

Abstract Preoperative exchange transfusion is a routine practice in patients with sickle cell disease having elevated sickle cell hemoglobin levels (>40%) undergoing open-heart surgery on cardiopulmon...

Neonatal Screening of Sickle Cell Anemia: A Preliminary Report.

OBJECTIVE: To evaluate feasibility of systematic neonatal screening for sickle cell disease in Chhattisgarh. METHODS:...

ED-based protocols speed care to sickle cell patients, reduce repeat ED visits, and discharge admitted patients earlier.

Patients with sickle cell disease commonly experience episodes of extreme pain that prompt them to seek care in the ED. However, emergency providers sometimes mistake these patients as drug-seekers, d...

Sickle Cell Disease: An Opportunity for Palliative Care Across the Life Span.

Sickle cell disease is a chronic illness that affects patients physically and emotionally and can do so at an early age. An ecological model of palliative care that involves improved communication amo...