Herpes simplex virus HSV 1 HSV 2 HHV 1 HHV 2

Herpes simplex virus 1 and 2 (HSV-1 and HSV-2), also known as Human herpes virus 1 and 2 (HHV-1 and -2), are two members of the herpes virus family that infect humans. HSV-1 and HSV-2 cause the vira...

Genital

Genital human papilloma virus HPV Vaccines

Genital human papilloma virus is one of the most common sexually transmitted infections (STI). Two vaccines are commercially available to protect females against the types of HPV that cause most cervi...

Genital Warts

Genital congestion

Glaxo genital herpes vaccine flops but Agenus a buy in vaccine space

By Rex Graham A Glaxo Smith Kline (Nasdaq: GSK) genital herpes vaccine recently flopped in a large clinical trial, but “next generation” genital herpes vaccines by Genocea Biosciences, Agenus, Inc...

Glaxo's Genital Herpes Vaccine Flops But Genocea's Next-Generation Approach Makes It A Buy

By Rex Graham:A GlaxoSmithKline (GSK) genital herpes vaccine recently flopped in a large clinical trial, but "next generation" genital herpes vaccines by Genocea Biosciences, Agenus, Inc. (AGEN), Vica...

Identification Of Immune Cells That Suppress Genital Herpes Infections Has Implications For Vaccine Development

Fred Hutchinson Cancer Research Center and University of Washington scientists have identified a class of immune cells that reside long-term in the genital skin and mucosa and are believed to be respo...

Yale researchers develop alternative vaccine strategy

Yale researchers have developed a new model for vaccination against genital herpes, a disease for which there has been no cure and no effective immunization. A vaccine strategy that protects against g...

New vaccine strategy may fight genital herpes, mouse study suggests

(HealthDay)—A new vaccination approach may provide protection against genital herpes as well as other sexually transmitted infections, including HIV, according to a new study involving mice.

Genital Herpes: Where's That Vaccine?

Sandra Fryhofer, MD, describes 2 disappointing studies on herpes simplex virus 2, showing that antiviral drugs don't stop it from spreading and there's still no vaccine. Medscape Internal Medicine

Vical's Herpes Vaccine: New Lab Results Confirm Move To The Clinic

By Theodore Cohen:In August 2011 and February 2012 I presented detailed overviews of Vical Incorporated's (VICL) herpes simplex virus type 2 or HSV-2 vaccine. Of the two serotypes identified, HSV-1 an...

Scientists identify new class of immune cells that suppress genital herpes

Fred Hutchinson Cancer Research Center and University of Washington scientists have identified a class of immune cells that reside long-term in the genital skin and mucosa and are believed to be respo...

Herpes Simplex Virus Genital Infections: Current Concepts.

Genital herpes is a common sexually transmitted disease that is frequently undiagnosed. Viral shedding occurs frequently and often without symptoms facilitating transmission to sex partners. Genital h...

Evaluation of a dominant-negative recombinant herpes simplex virus (HSV) type 1 as a vaccine against genital herpes in mice und guinea pigs.

Genital herpes caused by herpes simplex virus (HSV) is one of the most common sexually transmitted diseases worldwide. Currently, no safe and effective vaccine against HSV is available. CJ9-gD is a co...

Nasal and skin delivery of IC31(®)-adjuvanted recombinant HSV-2 gD protein confers protection against genital herpes.

Genital herpes caused by herpes simplex virus type 2 (HSV-2) remains the leading cause of genital ulcers worldwide. Given the disappointing results of the recent genital herpes vaccine trials in human...

A Vaxfectin(®)-adjuvanted HSV-2 plasmid DNA vaccine is effective for prophylactic and therapeutic use in the guinea pig model of genital herpes.

Here we describe studies in the guinea pig model of genital herpes to evaluate a novel plasmid DNA (pDNA) vaccine encoding the HSV-2 glycoprotein D and UL46 and UL47 genes encoding tegument proteins V...

Immunology. Painful failure of promising genital herpes vaccine.