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Search Results for "Beta Galactosidase Enzyme And Biosensor"

21:33 EDT 20th May 2013 | BioPortfolio

Original Source: β-galactosidase Determination by an Electrochemical Biosensor Mediated with Ferrocene.

Abstract: In this paper, a new viewpoint on the activity determination of β-galactosidase is reported. Glucose oxidase was directly immobilized on a glassy carbon electrode and mediated by ferrocene. The biosensor's performance was based on mediated electron transfer by ferrocene, which reduced via glucose oxidase reaction. In this reaction, substrate of glucose oxidase, glucose was provided by the activity of β-galactosidase in the sample. The parameters of the fabrication process for the electrode were...

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Eliglustat acts at a level above the defective enzyme in Gaucher disease and reduces the amount of a toxic metabolite (glucosylceramide) that is the target of enzyme replacement therapy.

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Transforming growth factor-beta (TGF-beta) family members are secreted multifunctional cytokines that play pivotal roles in development and disease. The prototypic member of this family, TGF-beta, pla...

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Cloning and characterization of a novel cold-active glycoside hydrolase family 1 enzyme with beta-glucosidase, beta-fucosidase and beta-galactosidase activities

Background: Cold-active enzymes, sourced from cold-adapted organisms, are characterized by high catalytic efficiencies at low temperatures compared with their mesophilic counterparts, which have poor...

Cloning, overexpression, purification, and characterization of a polyextremophilic beta-galactosidase from the Antarctic haloarchaeon Halorubrum lacusprofundi

Background: Halorubrum lacusprofundi is a cold-adapted halophilic archaeon isolated from Deep Lake, a perennially cold and hypersaline lake in Antarctica. Its genome sequencing project was recently co...

Cloning and characterization of a novel cold-active glycoside hydrolase family 1 enzyme with ß-glucosidase, ß-fucosidase and ß-galactosidase activities

Background: Cold-active enzymes, sourced from cold-adapted organisms, are characterized by high catalytic efficiencies at low temperatures compared with their mesophilic counterparts, which have poor...

Cloning, overexpression, purification, and characterization of a polyextremophilic ß-galactosidase from the Antarctic haloarchaeon Halorubrum lacusprofundi

Background: Halorubrum lacusprofundi is a cold-adapted halophilic archaeon isolated from Deep Lake, a perennially cold and hypersaline lake in Antarctica. Its genome sequencing project was recently co...

Vale Francois Jacob 1920-2013

Carl Zimmer with a wonderful tribute to Francois Jacob:...Strangest of all the mutants Jacob and Monod discovered were ones that produced beta-galactosidase and permease all the time, regardless of wh...

GSK, Amicus amend Fabry's disease deal

Amicus Therapeutics Inc. (NASDAQ:FOLD) and GlaxoSmithKline plc (LSE:GSK; NYSE:GSK) amended a 2010 deal that gave the pharma exclusive, worldwide rights to Amicus' Fabry's disease therapy migalastat. A...

Biosensor device can diagnose diseases better than doctors

A universal biosensor could take all the guesswork out of a visit to the doctor, leading to more accurate diagnoses and bette -More- 

Low-cost biosensor to detect contaminated water in developing nations

An interdisciplinary team of nine Arizona State University students participating in the 2012 International Genetically Engineered Machine (iGEM) competition have embarked on a campaign to help red...

Matching PubMed Articles

beta-Galactosidase from Lactobacillus pentosus: Purification, characterization and formation of galacto-oligosaccharides.

A novel heterodimeric beta-galactosidase with a molecular mass of 105 kDa was purified from crude cell extracts of the soil isolate Lactobacillus pentosus KUB-ST10-1 using ammonium sulphate fractionat...

β-galactosidase Determination by an Electrochemical Biosensor Mediated with Ferrocene.

Abstract: In this paper, a new viewpoint on the activity determination of β-galactosidase is reported. Glucose oxidase was directly immobilized on a glassy carbon electrode and mediated by ferrocene....

Discovery of new beta-D-galactosidase inhibitors via pharmacophore modeling and QSAR analysis followed by in silico screening.

Glycosidases, including beta-D-galactosidase, are involved in a variety of metabolic disorders, such as diabetes, viral or bacterial infections, and cancer. Accordingly, we were prompted to find new b...

Extracellular secretion in Bacillus subtilis of a cytoplasmic thermostable beta-galactosidase from Geobacillus stearothermophilus.

beta-Galactosidase catalyzes the hydrolysis of beta-galactosides into monosaccharides and is widely used in dairy processing. This study reports the extracellular secretion of a cytoplasmic thermostab...

The effect of high pressure homogenization on the activity of a commercial β-galactosidase.

High pressure homogenization (HPH) has been proposed as a promising method for changing the activity and stability of enzymes. Therefore, this research studied the activity of β-galactosidase before...

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