Blast Crisis Pages on BioPortfolio:

BioPortfolio - Blast Crisis
Efficacy and Safety of LBH589B in Adult Patients With Refractory Chronic Myeloid Leukemia (CML) in Accelerated Phase or Blast Phase (Blast Crisis) ...
http://www.bioportfolio.com/indepth/Blast_Crisis.html...

BioPortfolio.com - BioWeb MYLOTARG GEMTUZUMAB OZOGAMICIN mab17 ...
... ongoing tumors (GIST) studies CML in blast crisis, 5/ 10/ 01 Novartis Hematologic response (chronic phase): 88% Met accelerated phase, or in
Hematologic ...
http://www.bioportfolio.co.uk/cgi-bin/dialogserver.exe?DB=se...

Gleevec Resistance
Blast crisis is a phase of CML when cancer cells have not only the hallmark chromosomal ... In patients with blast crisis, resistance to Gleevec occurs in
...
http://www.bioportfolio.com/news/btech_041802_1.htm...

BioPortfolio's Cancer Conditions Specialized Searches
Blast Crisis · Bone Cancer · Bone Cysts · Bone Neoplasms · Brachytherapy Radiation Therapy · Brain Cancer · Brain Neoplasms · Brain Stem Neoplasms ...
http://www.bioportfolio.co.uk/web/cancer_list.html...

BioPortfolio Limited Stakeholder Insight: Chronic Leukemias - Is ...
Percentage of patients progressing to blast crisis CML 233 ... Blast crisis is the greatest area of unmet need in CML but may not be the most commercially ...
http://www.bioportfolio.com/cgi-bin/acatalog/2119.html...

BioPortfolio's Rare Diseases News Feed
Blast Crisis · Blastomycosis · Blood Platelet Disorders · Bone Neoplasms · Borrelia · Botulism · Brain Neoplasms · Brain Stem Neoplasms · Brenner Tumor ...
http://www.bioportfolio.co.uk/news/rare.shtml...

BioPortfolio News: - Novartis Tasigna(R) (nilotinib) Trial...
Efficacy data in patients with CML in blast crisis are not available.(5). For nilotinib summary of product characteristics, ...
http://www.bioportfolio.com/news/Novartis-Tasigna(R)-(niloti...

BioPortfolio - Hunton & Williams LLP - Profile
During blast crisis of chronic myelogenous leukemia (CML), abnormal...18th December, 2008. Division of Hematology-Oncology, Department of Medicine, ...
http://www.bioportfolio.com/biocorporate/24185-Hunton%252B&%...

BioPortfolio - UBASH3B - ubiquitin associated and SH3 domain ...
... and is a promising therapeutic target for reversing drug-resistance in chronic myeloid leukemia-blast crisis and acute myeloid leukemia cells. ...
http://www.bioportfolio.com/gene/84959-UBASH3B.html...

BioPortfolio - Leukemia Adult Acute - InDepth
Blast crisis. A multicenter, prospective, randomized study was conducted to compare a...6th January, 2010. - Blood. 2009 Dec 3;114(24):4917. ...
http://www.bioportfolio.com/indepth/Leukemia_Adult_Acute.pdf...

Results from other life science and pharmaceutical sites:

Chronic myelogenous leukemia - Wikipedia, the free encyclopedia
Blast crisis is the terminal phase of CML and clinically behaves like an acute leukemia. ... Blast crisis is the final phase in the evolution of CML, ...
http://en.wikipedia.org/wiki/Chronic_myelogenous_leukemia...

Chronic Myelocytic Leukemia (CML): Leukemias: Merck Manual Home ...
Eventually the leukemia cells undergo more changes, and the disease progresses to an accelerated phase and then inevitably to blast crisis. In blast crisis ...
http://www.merck.com/mmhe/sec14/ch176/ch176e.html...

The biology of CML blast crisis.
Although the pathogenic effects of most CML blast crisis secondary changes are still poorly understood, ample evidence suggests that the phenotype of CML ...
http://www.ncbi.nlm.nih.gov/pubmed/14982876...

Bone Marrow Transplantation - Lymphoid blast crisis of chronic ...
Lymphoid blast crisis of chronic myelogenous leukemia occurring more than 11 years after receiving an allogeneic bone marrow transplant for chronic ...
http://www.nature.com/bmt/journal/v31/n3/full/1703820a.html...

T-cell blast crisis in chronic myelogenous leukemia ...
T-cell blast crisis in chronic myelogenous leukemia is rare. We examined three patients (ages 35 to 72 years) in whom T-cell blast crisis developed 11 to 36
...
http://www.ncbi.nlm.nih.gov/pubmed/9024065...

BioMed Central | Full text | EVI1 activation in blast crisis CML ...
EVI1 activation in blast crisis CML due to juxtaposition to the rare 17q22 partner region as part of a 4-way variant translocation t(9;22) ...
http://www.biomedcentral.com/1471-2407/8/193/...

FTY720, a new alternative for treating blast crisis chronic ...
Blast crisis chronic myelogenous leukemia (CML-BC) and Philadelphia chromosome- positive (Ph1-positive) acute lymphocytic leukemia (ALL) are 2 fatal ...
http://www.ncbi.nlm.nih.gov/pubmed/17717597...

Sudden Extramedullary T-Lymphoblastic Blast Crisis in CML ...
27 May 2008 ... Abstract and Introduction: Imatinib treatment of CML can produce long-term remission and improve survival in most patients, but uncommon ...
http://www.medscape.com/viewarticle/571981...

Lymphoid blast crisis in chronic myeloid leukaemia.
Blast crisis as an initial or terminal manifestation of chronic myeloid leukemia . A study of 28 patients. Am J Med. 1976 Feb;60(2):209–220. ...
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1632557/...

Leukemia - Myeloid blast crisis evolving during imatinib treatment ...
Myeloid blast crisis evolving during imatinib treatment of an FIP1L1-PDGFR alpha -positive chronic myeloproliferative disease with prominent eosinophilia ...
http://www.nature.com/leu/journal/v19/n2/full/2403600a.html...

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