Synthesis and Release of Thyroid Hormones

Drug Delivery - news, views, blogs

Drug delivery is the method or process of administering a pharmaceutical compound to achieve a therapeutic effect in humans or animals.  Drug delivery technologies are patent protected formulat...

DNA-FISH Probes

Fluorescent in situ hybridization (FISH) is a sensitive and accurate technique that allows the detection of chromosome aberrations. In this method, a single-stranded fluorescent-labeled nucleic acid...

Disorders of Calcium Concentration

Calcium (Ca) is required for the proper functioning of muscle contraction, nerve conduction, hormone release, and blood coagulation. In addition, proper Ca concentration is required for various othe...

Spirometry Test

The gold standard in lung testing In the same way that blood pressure measurements provide a simple yet effective screening method for cardiovascular disease, spirometry tests can help to unmask t...

Edgemont launches new higher dose bupropion extended-release tablets

Edgemont Pharmaceuticals has launched a new formulation dose of bupropion extended-release tablets in a strength of 450mg dose.

Generic Bupropion XL Reevaluation Running Behind Schedule

FDA has received data from just one of four bioequivalence studies of 300 mg bupropion extended-release generics it requested by March from sponsors following Impax/Teva’s withdrawal of their generi...

TevaImpax generic Wellbutrin XL 300mg pulled from US market on non-bioequivalence grounds

Following a review of new data, the US Food and Drug Administration says these indicate that Budeprion XL 300mg (bupropion hydrochloride extended-release tablets), a generic version of UK pharma giant...

Generic Bupropion XL Must Be Retested; Teva/Impax 300 mg Withdrawn After Efficacy Concerns

In what appears to the first downgrade of a generic equivalency based on patient complaints, FDA changes the high dose of the Teva/Impax product from AB to BX. The four other generic manufacturers of...

Impax, Teva pull generic version of Wellbutrin XL 300 mg

Impax Laboratories Inc. (NASDAQ:IPXL) and Teva Pharmaceutical Industries Ltd. (NYSE:TEVA) pulled a generic version of antidepressant Wellbutrin XL 300 mg from the market after FDA determined the gener...

Wockhardt launches generic version of anti-depressant drug Wellbutrin® SR

PARSIPPANY, N. J.  and MUMBAI, India, Sept. 4, 2012 /PRNewswire/ -- Pharmaceutical and biotechnology major Wockhardt has received final approval from the United States Food & Drug Admini...

FDA Withdraws Approval of Generic Antidepressant

The antidepressant Budeprion XL 300 mg, a generic form of the extended-release bupropion hydrochloride, is not therapeutically equivalent to Wellbutrin XL 300 mg, the brand-name drug, says the FDA....

FDA Update: Budeprion XL 300 mg Not Therapeutically Equivalent to Wellbutrin XL 300 mg

October 3, 2012 -- The U.S. Food and Drug Administration (FDA) has reviewed new data that indicate Budeprion XL 300 mg (bupropion hydrochloride extended-release tablets), manufactured by Impax Laborat...

Inhibition of glutamate release by bupropion in rat cerebral cortex nerve terminals.

Central glutamate neurotransmission has been postulated to play a role in pathophysiology of depression and in the mechanism of antidepressants. The present study was undertaken to elucidate the effec...

Bupropion, an atypical antidepressant, induces endoplasmic reticulum stress and caspase-dependent cytotoxicity in SH-SY5Y cells.

Bupropion is an atypical antidepressant that is currently used as a smoking cessation aid. Bupropion interferes with monoamine reuptake and is potentially neurotoxic, although this is yet to be confir...

Bupropion decreases resting motor threshold: A case report.

BACKGROUND: Bupropion is associated with a dose-related increased seizure risk. This effect could correlate with a change in motor cortex excitability. Transcranial magnetic stimulation (TMS) can asse...

Bupropion can close KATP channel and induce insulin secretion.

Abstract Recently, a case of newborn infant with transient hyperinsulinism has been reported. This infant was reported to be free from typical perinatal risk factors of hyperinsulinism except for the...

Bupropion in the treatment of depression in Parkinson's disease.

ABSTRACTA 78-year-old female with a nine-year history of depression was hospitalized due to worsening depression and symptoms associated with Parkinson's disease (PD). Her motor abilities improved on...