Burkitt's Lymphoma

Lymphoma relapse

Lymphoma

Lymphoma is a cancer of the lymph nodes; classified as Hodgkin or non-Hodgkin lymphoma. Malignancy varies, and the prognosis can be from a few months to many years. Symptoms include enlarged lymph...

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Myc is the protein encoded by the MYC gene that activates the cell cycle

Myc is the protein encoded by the MYC gene that activates the cell cycle. It promotes cell replication through genetic coding for p14, inhibiting MDM2 and preventing the degradation of the pro-apopt...

Burkitt Lymphoma

Overview Burkitt lymphoma is a fast-growing type of B-cell non-Hodgkin’s lymphoma. Although it grows quickly, patients who receive prompt and effective treatment often experience good outcomes. Ther...

NIH study shows Burkitt lymphoma is molecularly distinct from other lymphomas

Scientists have uncovered a number of molecular signatures in Burkitt lymphoma, including unique genetic alterations that promote cell survival, that are not found in other lymphomas. These findings p...

New key element discovered in pathogenesis of Burkitt lymphoma

(Helmholtz Association of German Research Centres) Burkitt lymphoma is a malignant, fast-growing tumor that originates from a subtype of white blood cells of the immune system and often affects intern...

Recurrent mutation of the ID3 gene in Burkitt lymphoma identified by integrated genome, exome and transcriptome sequencing

Reiner Siebert and colleagues report whole-genome, whole-exome and transcriptome sequencing of Burkitt lymphomas. They identify recurrent mutations in several genes not previously known to be mutated...

Duke-led genome sequencing of Burkitt lymphoma reveals unique mutation

In the first broad genetic landscape mapped of a Burkitt lymphoma tumor, scientists at Duke Medicine (home to the Duke Cancer Institute) and their collaborators identified 70 mutations, including seve...

Burkitt lymphoma risk after transplantation highlighted

Solid organ transplant recipients have a significant risk for developing Burkitt lymphoma (BL), US researchers have found.

Burkitt lymphoma is associated with malaria infection: study

ATLANTA (Reuters Health) - Malaria may be associated with the development of Burkitt lymphoma as well as protection from it, researchers said here December 11 at ASH 2012, the annual meeting of th...

Study Suggests New Approaches to Burkitt Lymphoma

A new study revealed insights into how Burkitt lymphoma differs from other lymphomas. The researchers identified several cancer-related genes and pathways that could serve as targets for future treat...

Atypical Burkitt's lymphoma transforming from follicular lymphoma.

ABSTRACT: Amongst follicular lymphoma that transforms into a high-grade lymphoma, majority are diffuse large B cell lymphoma. Here we reported a rare atypical Burkitt's lymphoma transformation from an...

Risk factors and treatment of childhood and adolescent Burkitt lymphoma/leukaemia.

Burkitt lymphoma/leukaemia is the most common (40%) form of non-Hodgkin lymphoma that occurs in children and adolescents. The prognosis of advanced (disseminated) Burkitt lymphoma/leukaemia in childre...

Primary gastric burkitt lymphoma: a rare cause of intraabdominal mass in childhood.

Primary gastric lymphoma in the pediatric population is rare and the role of Helicobacter Pylori (H. Pylori) in its pathogenesis is unclear. In this report, we describe a case of non-Hodgkin's lymphom...

Burkitt Lymphoma and Atypical Burkitt or Burkitt-like Lymphoma: Should These be Treated as Different Diseases?

Burkitt lymphoma (BL) is a mature B-cell non-Hodgkin lymphoma with an aggressive clinical course. Since the advent of short, intensive, multiagent chemoimmunotherapy regimens, it has carried a favorab...

Concurrent development of "Burkitt-like" lymphoma and BCL-2-rearranged low-grade B cell lymphoma sharing the same germinal center origin.

B cell lymphoma, unclassifiable, with features intermediate between diffuse large B cell lymphoma and Burkitt lymphoma (BL) is a new entity in WHO classification 2008, and includes Burkitt-like transf...