Search Results for "Caffeic Acid Phenethyl Ester Uses"
Original Source: The potential usage of caffeic acid phenethyl ester (CAPE) against chemotherapy-induced and radiotherapy-induced toxicity.
Protection of the patients against the side effects of chemotherapy and radiotherapy regimens has attracted increasing interest of clinicians and practitioners. Caffeic acid phenethyl ester (CAPE), which is extracted from the propolis of honeybee hives as an active component, specifically inhibits nuclear factor κB at micromolar concentrations and show ability to stop 5-lipoxygenase-catalysed oxygenation of linoleic acid and arachidonic acid. CAPE has antiinflammatory, antiproliferative, antioxidant, cytos...
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Cholesteryl Ester Transfer Protein (CETP)
The Cholesteryl Ester Transfer Protein (CETP) facilitates the transfer of cholesterol from HDL to other lipoproteins including LDL, in exchange for triglycerides. The CETP mediated transfer of chole...
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Omthera asserts Epanova superiority but US filing delayed to next year
Omthera Pharmaceuticals is determined to show that Epanova, its free fatty acid formulation of omega-3 that contains both eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), is superior to Ama...
Amarin stock tumble: No respect or justified jitters?
Shares of Amarin tumbled for the third day likely over investors’ concerns about the future of the company's newly approved fish oil pill Vascepa (formerly AMR101), a semisynthetic, 96% ultra-p...
Polyphenols contained in food exert have various positive effects on human health, the absorption and metabolism of polyphenols in intestinal tract needs to be studied in order to estimate these effec...
This article appeared in the Jan. 14 issues of ADVANCE. 1. Prescribing information. (2012). Vascepa. Dublin, Ireland: Amarin Pharmaceuticals Ireland Ltd. 2. Jacobson, T.A. (2012). A new pure omega...
The AAPS Journal: Nonaqueous Gel for the Transdermal Delivery of a DTPA Penta-ethyl Ester Prodrug
Type: Original PaperDiethylenetriamine pentaacetic acid penta-ethyl ester, designated as C2E5, was successfully incorporated into a nonaqueous gel for transdermal delivery. The thermal and rheological...
Fish oil fails in large Phase III trial
Italian researchers reported that a once-daily 1 g dose of N-3 polyunsaturated fatty acids missed the primary endpoint in a Phase III trial in 12,513 patients with multiple cardiovascular risk factors...
Favorable preliminary results from XenoPort’s XP23829 Phase 1 trial on RRMS, psoriasis
XenoPort, Inc. announced today favorable preliminary results from a Phase 1 clinical trial in healthy adults designed to assess the pharmacokinetics (PK), safety and tolerability of single doses of fo...
Dietary Phenethyl Isothiocyanate Slows Tumor Progression in Mouse Breast Cancer Model
Addition of a natural plant compound to the diet of a breast cancer-mouse model slowed the development of tumors...
Matching PubMed Articles
A series of catechol ring-fluorinated derivatives of caffeic acid phenethyl amide (CAPA) were synthesized and screened for cytoprotective activity against H2O2 induced oxidative stress in human umbili...
Antioxidative activity of propolis extract in yeast cells.
The antioxidative activities of propolis and its main phenolic compounds, caffeic acid, p-coumaric acid, ferulic acid, and caffeic acid phenethyl ester, were investigated in the yeast Saccharomyces c...
A simple, reliable and sensitive method for the simultaneous determination of caffeic acid phenethyl ester (CAPE) and its metabolite caffeic acid (CA) in dog plasma was developed using liquid chromato...
Lipase-catalyzed caffeic acid phenethyl ester (CAPE) synthesis in ionic liquid, 1-ethyl-3-methylimidazolium bis[(trifluoromethyl)sulfonyl]imide ([Emim][Tf(2)N]), was investigated in this study. The ef...
Caffeic acid phenethyl ester (CAPE): correlation of structure and antioxidant properties.
Caffeic acid phenethyl ester (CAPE), a plant polyphenolic concentrated in honeybee propolis, has been found to be biologically active in a variety of pathways. The aim of this study was to determine t...
