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Search Results for "Caffeic Acid Structure"

21:04 EDT 21st May 2013 | BioPortfolio

Original Source: Caffeic acid phenethyl ester (CAPE): correlation of structure and antioxidant properties.

Caffeic acid phenethyl ester (CAPE), a plant polyphenolic concentrated in honeybee propolis, has been found to be biologically active in a variety of pathways. The aim of this study was to determine the antioxidant activity of CAPE using different methods such as total antioxidant activity by the thiocyanate method, 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulphonic acid radicals, 1,1-diphenyl-2-picryl-hydrazyl free radicals, N,N-dimethyl-p-phenylenediamine dihydrochloride radicals and superoxide anion radica...

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Crystal structure of the entire respiratory complex I

The atomic-resolution structure of the entire respiratory complex I is reported, with the resolution high enough to map out the locations and orientations of nearly all amino-acid side chains—some o...

Gastrointestinal absorption and metabolism of apple polyphenols ex vivo by the pig intestinal mucosa in the Ussing chamber

Polyphenols contained in food exert have various positive effects on human health, the absorption and metabolism of polyphenols in intestinal tract needs to be studied in order to estimate these effec...

How Stomach Bacterium Avoids Acid Revealed By Atomic-Resolution View Of A Receptor

University of Oregon scientists have discovered how the bacterium Helicobacter pylori navigates through the acidic stomach, opening up new possibilities to inactivate its disease-causing ability witho...

Genevac Evaporator can Handle Highly Corrosive Chemicals and Acids

Genevac's Acid-Resistant EZ-2 Plus Evaporator uses inert and corrosion-proof materials to enable it to withstand up to 6N Hydrochloric acid, 70% Nitric acid and most acid chlorides including thionyl c...

AAPS PharmSciTech: Formation of Itraconazole–Succinic Acid Cocrystals by Gas Antisolvent Cocrystallization

Type: Original PaperCocrystals of itraconazole, an antifungal drug with poor bioavailability, and succinic acid, a water-soluble dicarboxylic acid, were formed by gas antisolvent (GAS) cocrystallizati...

A stomatin dimer modulates the activity of acid-sensing ion channels

Stomatins govern membrane trafficking and ion channel activity. The banana-shaped stomatin-domain dimmers oligomerize into a cylindrical structure. A dynamic hydrophobic pocket at the concave side of...

Many proteins exist in a state of 'disorder' and yet are functional

For 100 years, the dogma has been that amino acid sequence determines protein folding and that the folded structure determines function. But researchers explain in a new study, a large class of protei...

Ajinomoto Company, Inc. Announces Amino Acid Pricing Structure Changes

Ajinomoto Company, Inc. (Ajinomoto) today announced an updated pricing structure for its pharmaceutical, cosmetic, and food-grade bulk amino acids. Due to the impact of ris...

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In vitro and in vivo antioxidant properties of chlorogenic acid and caffeic acid.

Dietary polyphenols are thought to be beneficial for human health as antioxidants. Coffee beans contain a common polyphenol, chlorogenic acid. Chlorogenic acid is the ester of caffeic acid and quinic...

Enzymatic transformation of caffeic acid with enhanced cyclooxygenase-2 inhibitory activity.

Convenient enzymatic transformation of the phenylpropanoid caffeic acid (1) with polyphenol oxidase originating from pear afforded three new oxidized metabolites, caffeoxynic acid (2), caffeicinic aci...

Synthesis of a series of caffeic acid phenethyl amide (CAPA) fluorinated derivatives: comparison of cytoprotective effects to caffeic acid phenethyl ester (CAPE).

A series of catechol ring-fluorinated derivatives of caffeic acid phenethyl amide (CAPA) were synthesized and screened for cytoprotective activity against H2O2 induced oxidative stress in human umbili...

Caffeic Acid Disturbs Monocyte Adhesion onto Cultured Endothelial Cells Stimulated by Adipokine Resistin.

Adipokines have been implicated in the pathogenesis of atherosclerosis via pro-inflammatory mechanisms contributing to insulin resistance. The adipokine resistin causes endothelium dysfunction, which...

Synthesis and dual biological effects of hydroxycinnamoyl phenylalanyl/prolyl hydroxamic acid derivatives as tyrosinase inhibitor and antioxidant.

We previously reported that caffeoyl-amino acidyl-hydroxamic acid (CA-Xaa-NHOH) acted as both a good antioxidant and tyrosinase inhibitor, in particular when caffeic acid was conjugated with proline o...

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