Calcium-dependent interaction of calcineurin with Bcl-2 in ...
Calcineurin, a calmodulin-dependent protein phosphatase, regulates transcription and possibly apoptosis. Previous studies demonstrated that in baby hamster ...
http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=pub...
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Positive about calcineurin : Article : Nature Reviews Immunology
According to new research published in Immunity, calcineurin is required for positive but not negative selection of developing T cells in the thymus. ...
http://www.nature.com/nri/journal/v4/n5/full/nri1360.html...
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Genetic loss of calcineurin blocks mechanical overload-induced ...
The serine/threonine phosphatase calcineurin is an important regulator of calcium-activated intracellular responses in eukaryotic cells. ...
http://www.ncbi.nlm.nih.gov/pubmed/15082723...
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Targeting calcineurin activation as a therapeutic strategy for T ...
In the T-cell lineage, calcineurin activation is important for pre–T-cell ... We observed sustained calcineurin activation in human B- and T-cell lymphomas ...
http://www.nature.com/nm/journal/v13/n6/abs/nm1588.html...
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Calcineurin enhances MAPK phosphatase-1 expression and p38 MAPK ...
To this end, we investigated the interconnectivity between calcineurin-mediated cardiac myocyte hypertrophy and p38 MAPK signaling in vitro and in vivo. ...
http://www.ncbi.nlm.nih.gov/pubmed/11279073...
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Linking calcineurin activity to leukemogenesis : Article : Nature ...
Inhibition of calcineurin leads to a rapid clearance of leukemic cells and ... The signaling pathway leading to calcineurin activation begins with an influx
...
http://www.nature.com/nm/journal/v13/n6/full/nm0607-669.html...
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Calcineurin triggers reactive/inflammatory processes in astrocytes ...
Here, we studied the Ca2+-dependent phosphatase calcineurin, which regulates inflammatory signaling pathways in immune cells, for a role in astrogliosis and
...
http://www.ncbi.nlm.nih.gov/pubmed/15872113...
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Nature Clinical Practice Nephrology | A new pathologic scoring ...
(2007) A novel, semiquantitative, clinically correlated calcineurin inhibitor toxicity score for renal allograft biopsies. Clin J Am Soc Nephrol 2: 135–142
...
http://www.nature.com/ncpneph/journal/v3/n6/full/ncpneph0493...
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Genetic Polymorphisms and the Pharmacokinetics of Calcineurin ...
Evaluating polymorphisms in renal transplant recipients may help achieve better outcomes.
http://www.medscape.com/viewarticle/549094_2...
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Nature Clinical Practice Nephrology | Is it premature to use ...
Calcineurin-inhibitor nephrotoxicity is believed to contribute to the progression of ... To assess the efficacy and safety of a calcineurin-inhibitor-
free ...
http://www.nature.com/ncpneph/journal/v3/n1/full/ncpneph0361...
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