Top 50 Biopharma Products 2011

Ronald A. Rader, president of the Biotechnology Information Institute provided Contract Pharma a list of the Top 57 Biopharma Products by 2011 revenues (in millions). Mr. Rader subscribes to the sam...

CATT study clarifies value of genetic testing for age-related macular degeneration

New findings from a landmark clinical trial show that although certain gene variants may predict whether a person is likely to develop age-related macular degeneration (AMD), a potentially blinding ey...

Avastin unraveled by stratification study, Roche seeks validation

Reanalysis of Avastin registration trial brings Roche strategy for making universal Avastin use in oncology into question again. Study suggests less than half of Avastin treated colorectal cancer pat...

ASCO: continued Avastin after progression increases overall survival in colon cancer

In metastatic colorectal cancer patients who had a follow-up round of second-line Roche/Genentech’s Avastin (bevacizumab) after their disease worsened following initial Avastin plus first-line c...

Avastin Wins FDA Approval For Colorectal Cancer Treatment

The U.S. Food and Drug Administration (FDA) has approved use of Roche's Avastin for patients with colorectal cancer that has gotten worse despite treatment with the medication. This new approval will...

Major clinical trial finds no link between genetic risk factors and 2 top wet AMD treatments

New findings from a landmark clinical trial show that although certain gene variants may predict whether a person is likely to develop age-related macular degeneration (AMD), a potentially blinding ey...

Roche's Avastin Approved For Colon Cancer Treatment By FDA

The U.S. Food and Drug Administration (FDA) has approved use of Roche's Avastin for patients with colorectal cancer that has gotten worse despite treatment with the medication. This new approval will...

Continued Avastin Extends Survival After First Progression in Advanced Colorectal Cancer

Combined second-line treatment with Avastin® (bevacizumab) and standard chemotherapy extends survival in patients with advanced colorectal cancer who have received first-line combined Avastin treatme...

CATT at 2 Years: The Facts

Confirmation of our clinical observations is welcome for the future of AMD treatment. Medscape Ophthalmology

Unrecognized hospital trauma as a source of complex psychiatric symptoms: A systematic case study with implications for children's rights and evidence-based practice.

Abstract This article describes the psychological assessment and treatment of Paul (12). For several years, he had received numerous diagnoses from a range of specialists and been unsuccessfully treat...

FDA. Once on 'fast track,' avastin now derailed.

Ranibizumab: A Review of Its Use in the Treatment of Neovascular Age-Related Macular Degeneration.

Ranibizumab (Lucentis(®)), an inhibitor of all vascular endothelial growth factor (VEGF) A isoforms, is approved for the intravitreal treatment of neovascular age-related macular degeneration (AMD)....

Changing End Points in Breast-Cancer Drug Approval - The Avastin Story.

In December 2007, the Oncologic Drugs Advisory Committee (ODAC) of the Food and Drug Administration (FDA) met to discuss the risks and benefits of Genentech's Avastin (bevacizumab) for use in combinat...

Bevacizumab (Avastin) in central retinal vein occlusion.