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SIGN calls for monitoring of patients on antipsychotics

A timetable for monitoring the physical health of adult patients with schizophrenia should be established at the time they are first prescribed antipsychotic drugs, according to a new Scottish clinic...

Study Results Show PREPOPIK™ (Sodium Picosulfate, Magnesium Oxide, And Anhydrous Citric Acid) Demonstrates Successful Colon Cleansing With The Lowest Active Prep Solution Of Any Prescription Bowel Prep

PARSIPPANY, N.J., Oct. 22, 2012 /PRNewswire/ -- Ferring Pharmaceuticals Inc. has announced the presentation at the American College of Gastroenterology (ACG) 2012 Annual Scientific Meeting o...

Even today, morphine remains a popular opioid analgesic for cancer-related pain

Although it has a bad reputation for its addictive and side effects, morphine is still one of the best strong painkillers around. Jenny Bryan takes a look at the history of this drug Over 200 year...

Promazine and chlorpromazine for prolonged spinal anesthesia in rats.

Though promazine and chlorpromazine elicited cutaneous anesthesia, no study of spinal anesthesia with chlorpromazine and promazine has been reported. This study was to examine whether chlorpromazine a...

Intrathecal chlorprothixene, cis(z)-flupenthixol, chlorpromazine and fluphenazine for prolonged spinal blockades of sensory and motor functions in rats.

The aim of this study was to examine whether thioxanthine-type antipsychotics (chlorprothixene and cis(z)-flupenthixol) and phenothiazine-type antipsychotics (chlorpromazine and fluphenazine) produced...

Effects of phenothiazine-class antipsychotics on the function of α7-nicotinic acetylcholine receptors.

The effects of phenothiazine-class antipsychotics (chlorpromazine, fluphenazine, phenothiazine, promazine, thioridazine, and triflupromazine) upon the function of the cloned α(7) subunit of the human...

Development of a negligible depletion-solid phase microextraction method to determine the free concentration of chlorpromazine in aqueous samples containing albumin.

The addition of proteins to in vitro systems influences the free concentration of the test compound in the medium. The objective of this study was to set up a negligible depletion-solid phase microext...

Inhibitory Effects of Psychotropic Drugs on the Acetylcholine Receptor-Operated Potassium Current (I(K.ACh)) in Guinea-Pig Atrial Myocytes.

Influences of psychotropic drugs, six antipsychotics and three antidepressants, on acetylcholine receptor-operated potassium current (I(K.ACh)) were examined by a whole-cell patch clamp method in fres...