Search Results for "Cns Vasculitis Mechanism"
Original Source: Primary central nervous system vasculitis: pathology and mechanisms.
Primary vasculitis of the central nervous system (PCNSV) is a rare and diagnostically challenging form of vasculitis limited to the brain and/or spinal cord. It is a complex and often severe disease with multifaceted clinical and pathological appearances, suggesting multiple disease subtypes and the potential existence of multiple etiologic pathways. We describe in detail the clinical, imaging, and neuropathological findings of PCNSV summarizing literature data and our observations from a cohort of 131 pati...
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Vasculitis (plural: vasculitides) refers to a heterogeneous group of disorders that are characterized by inflammatory destruction of blood vessels. Vasculitis is primarily due to leukocyte migration...
Acute transverse myelitis is acute inflammation of gray and white matter in one or more adjacent spinal cord segments, usually thoracic. Causes include multiple sclerosis, infections, autoimmune or...
Rheumatology is the medical specialty concerned with the diagnosis and management of disease involving joints, tendons, muscles, ligaments and associated structures (Oxford Medical Dictionary). It...
ETS2101 (dexanabinol) is a synthetic cannabinoid previously studied in trauma patients. Its anti-cancer potential was identified by e-Therapeutics’ network pharmacology platform. This revealed...
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Vasculitis: Biomarkers for staging ANCA-associated vasculitis activity
Gene Variants Linked to Rare Vasculitis (CME/CE)
(MedPage Today) -- The two primary types of vasculitis associated with anti-neutrophil cytoplasmic antibodies have a strong genetic component, a genome-wide association study showed.
Maintenance immunosuppression may help in vasculitis subgroup
NEW YORK (Reuters Health) - Patients with early systemic cytoplasm antibody-associated vasculitis (AAV) tend to have better relapse-free survival over the long term with cyclophosphamide rather th...
Glucocorticoids Key in Vasculitis Trial (CME/CE)
SAN DIEGO (MedPage Today) -- Mycophenolate mofetil (CellCept) proved non-inferior to cyclophosphamide (Cytoxan) for treating ANCA-associated vasculitis in a regimen that permitted use of glucocorticoi...
Steroids, Relapse Predict Damage from Vasculitis (CME/CE)
(MedPage Today) -- BIRMINGHAM, England -- Patients with systemic vasculitis who require steroids for long periods or who have multiple relapses are likely to have extensive, irreversible organ damage,...
Rituximab Works in ANCA-Linked Vasculitis (CME/CE)
WASHINGTON (MedPage Today) -- Rituximab given as adjunctive therapy to children with antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis dramatically lowered the dosage of cyclophosphamid...
GlaxoSmithKline announces commencement of phase III study of vasculitis drug
GlaxoSmithKline has announced the commencement of phase III study of Benlysta (belimumab) in patients with ANCA (Anti-neutrophil Cytoplasmic Antibodies) positive vasculitis.
Renal vasculitis in 2012: Reclassification and the introduction of biologicals
2012 saw the classification of the systemic vasculitides revised. Genetic studies showed that granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA) are different diseases with aber...
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Remarks on the Asia Pacific Meeting of Vasculitis and ANCA Workshop 2012.
An international meeting, The Asia Pacific Meeting of Vasculitis and ANCA Workshop 2012, was held on March 28-31, 2012 at Shinagawa, Tokyo, Japan. The meeting focused on vasculitis and anti-neutrophil...
We report a case of thrombotic thrombocytopenic purpura (TTP) secondary to antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis treated by rituximab. TTP secondary to ANCA-associated vascu...
OBJECTIVES: /st> To compare the Vasculitis Damage Index (VDI) with the Combined Damage Assessment Index (CDA) as measures of damage from vasculitis. METHODS: /st> A total of 283 patients with vasculit...
Propylthiouracil-induced autoimmune syndromes: 11 case report.
The objective of this study was to report 11 cases of propylthiouracil (PTU)-induced autoimmune syndromes. We describe the clinical presentation, course, and outcome of 11 patients and compare clinica...
Rheumatoid Vasculitis: Vanishing Menace or Target for New Treatments?
Rheumatoid vasculitis is a rare but serious complication of rheumatoid arthritis. Herein we examine the pathophysiology, epidemiology, clinical diagnosis, and treatment of rheumatoid vasculitis. Serop...
