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11:40 EST 8th February 2016 | BioPortfolio

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Uveitis

There are many different types of Uveitis. This is because: * The Uvea is made up of different parts. So if the iris is affected, the condition and its treatment could be totally different to when...

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How cocaine changes the brain

The burst of energy and hyperactivity that comes with a cocaine high is a rather accurate reflection of what's going on in the brain of its users, finds a study. Through experiments conducted in rats ...

New insights on how cocaine changes the brain

The burst of energy and hyperactivity that comes with a cocaine high is a rather accurate reflection of what's going on in the brain of its users, finds a study published November 25 in Cell Reports. ...

Magnetic Brain Stimulation Might Treat Cocaine Addiction

THURSDAY, Dec. 3, 2015 -- Stimulating part of the brain with magnetic pulses may offer the first therapeutic treatment for cocaine addiction, a small new study suggests. Though the findings are prelim...

Mouse Study Shows Cocaine Ravages Brain Cells

MONDAY, Jan. 18, 2016 -- In mice, high doses of cocaine cause brain cells to eat themselves, researchers report. The Johns Hopkins University scientists also found such destruction in the brain cells ...

Cocaine Induces Neuronal Autophagy

A new study supports the idea that cocaine triggers brain cells to eat themselves and suggests a possible antidote.

Magnetic stimulation of brain may help patients with cocaine addiction

Targeted magnetic pulses to the brain were shown to reduce craving and substance use in cocaine-addicted patients, report scientists. The results of this pilot study suggest that this may become an ef...

New enzyme therapy shows proof of concept as treatment for cocaine overdose

(American Association of Pharmaceutical Scientists) A long-acting enzyme that rapidly and safely metabolizes cocaine in the blood stream is currently being investigated in animal models as a possible ...

New York drug bust nets 136 pounds of cocaine worth estimated $3 million

Mark Soto and Xavier Herbert-Gumbs, face felony drug possession charges after authorities said they found a total of 136 pounds (61.7 kg) of cocaine in their vehicles in the Bronx, according to a stat...

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Oxytocin Decreases Cocaine Taking, Cocaine Seeking, and Locomotor Activity in Female Rats.

Oxytocin has been shown to decrease cocaine taking and seeking in male rats, suggesting potential treatment efficacy for drug addiction. In the present study, we extended these findings to the assessm...

Activin receptor signaling regulates cocaine-primed behavioral and morphological plasticity.

Activin receptor signaling, including the transcription factor Smad3, was upregulated in the rat nucleus accumbens (NAc) shell following withdrawal from cocaine. Direct genetic and pharmacological man...

Oral fluid cocaine and benzoylecgonine concentrations following controlled intravenous cocaine administration.

Limited oral fluid (OF) pharmacokinetic data collected with commercially available collection devices after controlled cocaine administration hinder OF result interpretations. Ten cocaine-using adults...

Cyclosporine eye drops: A 4-year retrospective study (2009-2013).

The University Hospitals Paris Centre Pharmacy compounds three concentrations of cyclosporine eye drops: 20mg/mL (=2%); 5mg/mL (=0.5%) and 0.5mg/mL (=0.05%). Cyclosporine A 2% drops were developed in ...

Cocaine-induced reward enhancement measured with intracranial self-stimulation in rats bred for low versus high saccharin intake.

Rats selectively bred for high (HiS) or low (LoS) saccharin intake are a well-established model of drug-abuse vulnerability, with HiS rats being more likely to consume sweets and cocaine than LoS rats...

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