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19:08 EDT 4th September 2015 | BioPortfolio

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Uveitis

There are many different types of Uveitis. This is because: * The Uvea is made up of different parts. So if the iris is affected, the condition and its treatment could be totally different to when...

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Role of Tet1 and 5-hydroxymethylcytosine in cocaine action

Expression of TET1 dioxygenase, which catalyzes the conversion of 5-methylcytosine to 5-hydroxymethylcytosine, is downregulated by repeated cocaine administration in mouse nucleus accumbens, where it ...

Prenatal cocaine exposure linked to adolescents engaging in sex by age 15

Since 1994, researchers have studied mothers -- some who used cocaine while pregnant and others who did not -- to understand how the drug affected their children's cognitive and social development . T...

Researchers Discover How Cocaine, Amphetamines Disrupt the Brain’s Normal Functioning

In a major advance in the field of neuropsychiatry, researchers in the Vollum Institute at Oregon Health & Science University have illuminated how cocaine and amphetamines disrupt the normal funct...

Cocaine changes brains makes relapse more common in addicts

Cocaine use causes ‘profound changes’ in the brain that lead to an increased risk of relapse due to stress, according to new research that identifies a molecular mechanism in the reward centre of ...

Researchers discover how cocaine, amphetamines disrupt the brain's normal functioning

In a major advance in the field of neuropsychiatry, researchers in the Vollum Institute at Oregon Health & Science University have illuminated how cocaine and amphetamines disrupt the normal functioni...

Brain receptor found to affect cocaine addiction

Researchers at the Univ. at Buffalo have discovered a previously unknown neural pathway that can regulate changes made in the brain due to cocaine use, providing new insight into the molecular basis o...

Cocaine changes brain, makes relapse more common in addicts

Cocaine use causes 'profound changes' in the brain that lead to an increased risk of relapse due to stress, according to new research that identifies a molecular mechanism in the reward centre of the ...

More evidence for possible link between cocaine use and HIV infection

New UCLA research offers further evidence that cocaine use disrupts the immune system, making people who use it more likely to become infected with HIV.

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Cocaine Dependence and Stroke: Pathogenesis and Management.

Cocaine abuse remains a devastating medical problem for our society. Current concepts suggest that both hemorrhagic and ischemic stroke, particularly in young people, can result as a consequence of co...

The Magnitude of Drug Attentional Bias Is Specific to Substance Use Disorder.

The visual probe task with eye tracking is a sensitive measure of cocaine and alcohol cue attentional bias. Despite the high comorbidity between cocaine and alcohol dependence, attentional bias studie...

Quetiapine for the treatment of cocaine use disorder.

Cocaine addiction continues to be a significant healthcare issue, yet there are no FDA approved medications for the treatment of cocaine use disorder within the United States.

Activin receptor signaling regulates cocaine-primed behavioral and morphological plasticity.

Activin receptor signaling, including the transcription factor Smad3, was upregulated in the rat nucleus accumbens (NAc) shell following withdrawal from cocaine. Direct genetic and pharmacological man...

Effects of the kappa opioid receptor antagonist nor-binaltorphimine (nor-BNI) on cocaine versus food choice and extended-access cocaine intake in rhesus monkeys.

The dynorphin/kappa opioid receptor (KOR) system has been implicated as one potential neurobiological modulator of the abuse-related effects of cocaine and as a potential target for medications develo...

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