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10:41 EDT 20th August 2014 | BioPortfolio

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Uveitis

There are many different types of Uveitis. This is because: * The Uvea is made up of different parts. So if the iris is affected, the condition and its treatment could be totally different to when...

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Use of cocaine drops and marijuana increases across the United States

The use of cocaine dropped sharply across the United States from 2006 to 2010, while the amount of marijuana consumed increased significantly during the same period, according to a new report.

Cocaine, pleasure principle explored in new rat study

On the other side of the cocaine high is the cocaine crash, and understanding how one follows the other can provide insight into the physiological effects of drug abuse. For decades, brain research ha...

Mutated Cocaine Esterase Enzyme can be the Potential Cure for Cocaine Overdoses

A mutated enzyme is now the newest weapon in the battle against cocaine overdoses and addiction. Cocaine esterase is a natural enzyme that breaks cocaine down into its inactive components. However, th...

UCSB study explores cocaine and the pleasure principle

(University of California - Santa Barbara) On the other side of the cocaine high is the cocaine crash, and understanding how one follows the other can provide insight into the physiological effects of...

Animal models demonstrate that the net result of cocaine use is a balance of both positive and negative effects

On the other side of the cocaine high is the cocaine crash, and understanding how one follows the other can provide insight into the physiological effects of drug abuse. For decades, brain research ha...

Cocaine-Busting, Mutant Enzyme Could Treat Overdoses

In the battle against cocaine overdoses and addiction, say hello to scientists’ little friend: a mutated enzyme with an appetite for coke. Roughly 500,000 people visit the emergency room every year...

Social cocaine use more harmful than you think

(Medical Xpress)—In addition to recent high profile cocaine possession arrests and the Australian Crime Commission's Illicit Drug Data Report 2012-2013 being released today, University of Sydney res...

Subtle changes may occur in neural circuits due to cocaine addiction

Evidence shows that subtle changes of inhibitory signaling in the reward pathway can change how animals respond to drugs such as cocaine. This is the first study to demonstrate the critical links betw...

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Powder and Crack Cocaine Use Among Opioid Users: Is All Cocaine the Same?

Problematic cocaine use is highly prevalent and is a significant public health concern. However, few investigations have distinguished between the 2 formulations of cocaine (ie, powder and crack cocai...

Multiple gastrointestinal complications of crack cocaine abuse.

Cocaine and its alkaloid free base "crack-cocaine" have long since been substances of abuse. Drug abuse of cocaine via oral, inhalation, intravenous, and intranasal intake has famously been associated...

A thermostable bacterial cocaine esterase rapidly eliminates cocaine from brain in nonhuman primates.

A long-acting, thermostable bacterial cocaine esterase (CocE) has been identified that rapidly degrades cocaine with a KM of 1.33+0.085 μM. In vivo evaluation of CocE has shown protection against c...

Evaluation of clinical outcomes in patients with dry eye disease using lubricant eye drops containing polyethylene glycol or carboxymethylcellulose.

The purpose of this study was to compare changes in corneal staining in patients with dry eye after 6 weeks of treatment with Systane® Gel Drops or Refresh Liquigel® lubricant eye drops.

Changes in microRNA expression profile in hippocampus during the acquisition and extinction of cocaine-induced conditioned place preference in rats.

MicroRNA (miRNA) emerges as important player in drug abuse. Yet, their expression profile in neurological disorder of cocaine abuse has not been well characterized. Here, we explored the changes of mi...

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